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tag european medicines agency evolution

A pregnant woman gets her blood pressure checked by a doctor
U.K. Health Authority Investigates Epilepsy Drug’s Link to Autism
Peter Hess, Spectrum | Aug 30, 2022 | 3 min read
The Medicines and Healthcare products Regulatory Agency’s investigation comes after a study showed prenatal exposure to topiramate roughly triples a child’s likelihood of having autism or intellectual disability.
Adaptive Evolution
Alla Katsnelson | Aug 1, 2009 | 7 min read
By Alla Katsnelson Adaptive Evolution A once-rare type of clinical trial that violates one of the sacred tenets of trial design is taking off, but is it worth the risk? Doriano Solinas When researchers at Pfizer first began a Phase 2 trial of an acute stroke therapy in 2000, they decided to take a novel approach. The study—called the ASTIN trial—would determine the drug’s optimal dose not with three or four diffe
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
A photo of King Charles III, then formally Prince of Wales, wearing a dark suit, shown from the shoulders up.
The Unscientific King: Charles III’s History Promoting Homeopathy
Sophie Fessl, PhD | Sep 29, 2022 | 6 min read
King Charles III has a long history of promoting homeopathic or alternative medical treatments not supported by scientific evidence.
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
Week in Review: June 16–20
Tracy Vence | Jun 20, 2014 | 2 min read
Early Neanderthal evolution; developing antivirals to combat polio; the mouth and skin microbiomes; insect-inspired, flight-stabilizing sensors
Week in Review: March 27–31
Tracy Vence | Mar 31, 2017 | 3 min read
European Patent Office greenlights CRISPR patent; scientists reconsider a cancer drug target; NIH accepts preprints in grant applications; MERS drug developers test antibodies; experts weigh the risks and benefits of whole-exome sequencing for healthy people
Collage of those featured in the article
Remembering Those We Lost in 2021
Lisa Winter | Dec 23, 2021 | 5 min read
As the year draws to a close, we look back on researchers we bid farewell to, and the contributions they made to their respective fields.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Congress' Pusillanimity Prevents Real FDA Reform
Henry Miller | Dec 7, 1997 | 4 min read
Congress has lost a stunning opportunity to reform the Food and Drug Administration (FDA). The authorization for the agency's critical "user fees"-approximately $100 million paid annually by regulated industry to help FDA expedite the approval of new medicines-expired on October 1. The need for another five-year reauthorization provided a strong incentive for the Clinton administration to accept meaningful reforms. Characteristically, however, the Congress settled for a half-baked compromise di

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