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image: Toward a Nonaddictive Opioid

Toward a Nonaddictive Opioid

By | August 18, 2016

A newly discovered painkiller does not cause respiratory depression or addiction in mice and could be an alternative to frequently abused prescription medicines, researchers report.

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image: Toward a Cocaine Vaccine

Toward a Cocaine Vaccine

By | January 22, 2015

A modified bacterial protein elicits a robust immune response against a cocaine-linked molecule in mice.

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image: Chronic Weed Use Shrinks Brain Region

Chronic Weed Use Shrinks Brain Region

By | November 12, 2014

Long-term marijuana smokers have less gray matter in their orbitofrontal cortex than nonsmokers, but other brain circuits may compensate by increasing connectivity.

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image: An Offensive Playbook

An Offensive Playbook

By | February 1, 2014

Developing nonaddictive drugs to combat pain

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image: Pain and Progress

Pain and Progress

By | February 1, 2014

Is it possible to make a nonaddictive opioid painkiller?

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image: Suppressing Drug-Seeking Behaviors

Suppressing Drug-Seeking Behaviors

By | November 24, 2013

Augmenting the action of a glutamate receptor in the brains of addicted rats helps prevent them from seeking cocaine during withdrawal, a study shows.

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image: The Epigenetics of Drug Abuse

The Epigenetics of Drug Abuse

By | November 11, 2013

At the Society for Neuroscience conference, researchers present results linking the epigenome to heroin and cocaine addiction.

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image: Get Off the Pot

Get Off the Pot

By | October 15, 2013

Researchers demonstrate the successful treatment of marijuana abuse in rats and monkeys.

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image: Natural Opioids Linked to Chronic Pain

Natural Opioids Linked to Chronic Pain

By | September 19, 2013

The body’s own pain-quelling system may be at the root of chronic pain and symptoms of opioid withdrawal, according to a new study in mice.

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image: HIV Protein Boosts Cocaine's Effect

HIV Protein Boosts Cocaine's Effect

By | August 15, 2013

Mice whose brains express the HIV-1 Tat protein show a heightened response to the drug and appear more vulnerable to relapse.

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