Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

Standing at the cornerstone of genetic research, Cre-loxP recombination serves as molecular scissors for precisely manipulating the genome.

Scientists transferred light-harvesting proteins into yeast for the first time, shining a light on the past lives of eukaryotic cells.

Studies have found that organisms can inherit mitochondria from male parents in rare instances, and both theoretical and experimental work hint that this biparental inheritance is more than just a fluke.

This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.

The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.

With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.

Whole genome sequences reveal multiple domestications of this agriculturally important tree and may hold the secrets to producing the sweet fruit year round.

Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.

Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.