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tag heart failure microbiology immunology genetics genomics

Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
Resistant to Failure
Cristina Luiggi | Feb 28, 2011 | 3 min read
A Duke University researcher survives a sticky situation at a federal research institution to make major strides in determining the genetic roots of Staphylococcus aureus antibiotic resistance.
mouse in grass microbiome
New Mouse Model Predicts Two Clinical Trial Failures in Humans
Emma Yasinski | Aug 1, 2019 | 4 min read
The lab animals had more natural microbiomes seeded by wild mice, unlike conventional models that are kept in sterile conditions.
Fluorescent images of red cells showing high and low levels of infection in green
Parasite Drove Natural Selection in Amazonian Indigenous Groups
Natalia Mesa, PhD | Mar 13, 2023 | 4 min read
The findings could help researchers understand why some individuals are more vulnerable to deadly Chagas disease.
Top 7 in Immunology
Edyta Zielinska | Aug 2, 2011 | 3 min read
A snapshot of the most highly ranked articles in microbiology and related areas, from Faculty of 1000
A white coat-wearing doctor holds the results of an EKG test in one hand and traces over them with a pen in the other hand
Doctors and Researchers Probe How COVID-19 Attacks the Heart
Dan Robitzski | Jan 12, 2022 | 8 min read
Experts have a decent grasp on how COVID-19 impacts cardiovascular health in the near term. The implications of long COVID, however, remain mysterious.
Immune to Failure
Karen Hopkin | Feb 1, 2013 | 9 min read
With dogged persistence and an unwillingness to entertain defeat, Bruce Beutler discovered a receptor that powers the innate immune response to infections—and earned his share of a Nobel Prize.
Bright purple and orange lactobacillus bacteria.
How a Specific Gut Bacterium May Cause Type 1 Diabetes
Dan Robitzski | Aug 25, 2022 | 5 min read
A bacterium that produces an insulin-like peptide can give mice type 1 diabetes, and infection with the microbe seems to predict the onset of the disease in humans, a study finds.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.

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