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tag heart failure disease medicine

HEART FAILURE
Christopher Michael O'connor | Oct 11, 1998 | 2 min read
M. Packer, C.M. O'Connor, J.K. Ghali, M.L. Pressler, P.E. Carson, R.N. Belkin, A.B. Miller, G.W. Neuberg, D. Frid, J.H. Wertheimer, A.B. Cropp, D.L. DeMets, "Effect of amlodipine on morbidity and mortality in severe chronic heart failure," New England Journal of Medicine, 335:1107-14, 1996. (Cited in more than 155 papers since publication) Comments by Christopher Michael O'Connor, associate director of the Duke Clinical Research Institute, Durham, N.C. Medical advances have allowed us to live
ADAMs cut into heart failure
Tudor Toma(t.toma@ic.ac.uk) | Dec 30, 2001 | 1 min read
Cardiac hypertrophy is an adaptive response to an increase in blood pressure which, despite initial benefits, leads to heart failure and is an independent risk factor for cardiovascular disease. In January Nature Medicine, Masanori Asakura and colleagues from Osaka University Faculty of Medicine, Osaka, Japan show that shedding of heparin-binding epidermal growth factor (HB-EGF) by ADAM12 plays an important role in the development of cardiac hypertrophy.Asakura et al. found that in cultured rat
Heart Disease
The Scientist Staff | Jun 20, 1999 | 3 min read
Edited by: Nadia S. Halim B. Pitt, R. Segal, F.A. Martinez, G. Meurers, A.J. Cowley, I. Thomas, P.C. Deedwania, D.E. Ney, D.B. Snavely, P.I. Chang, "Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE)," The Lancet, 349:747-52, 1997. (Cited in more than 230 papers since publication) Comments by Bertram Pitt, professor of medicine, division of cardiology, University of Michigan, Ann Arbor, and Robert Segal, dir
Power Failure
Megan Scudellari | May 1, 2011 | 10+ min read
Does mitochondrial dysfunction lie at the heart of common, complex diseases like cancer and autism?
knitted pink heart with a mended hole
CAR T Cells Mend Broken Mouse Hearts
Sophie Fessl, PhD | Jan 6, 2022 | 4 min read
Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.
A white coat-wearing doctor holds the results of an EKG test in one hand and traces over them with a pen in the other hand
Doctors and Researchers Probe How COVID-19 Attacks the Heart
Dan Robitzski | Jan 12, 2022 | 8 min read
Experts have a decent grasp on how COVID-19 impacts cardiovascular health in the near term. The implications of long COVID, however, remain mysterious.
a spiny mouse sits on a piece of wood holding a small morsel to its mouth
Spiny Mice Appear to Regenerate Damaged Kidneys
Dan Robitzski | Nov 3, 2021 | 5 min read
The mice, already known to regenerate skin, seem to avoid the tissue scarring that leads to organ failure in other animals.
Power Failure
Megan Scudellari | May 1, 2011 | 10+ min read
Power Failure Does mitochondrial dysfunction lie at the heart of common, complex diseases like cancer and autism? Kevin Hand Mitochondria are tiny. A single human cell can contain hundreds to thousands of these potato-shaped organelles, depending on the tissue type. They power the biochemical reactions in our cells through the production of adenosine triphosphate (ATP). These oft-overlooked furnaces, not studied in earnest until the 19
An illustration of a pregnant women wearing a mask, surrounded by microbes
How COVID-19 Affects Pregnancy
Amanda Heidt | Aug 16, 2022 | 10 min read
Evidence thus far shows that pregnant people infected with SARS-CoV-2 are at higher risk for severe disease and death, as well as complications in their pregnancies.
Making a Play at Regrowing Hearts
Kenneth Chien | Aug 1, 2006 | 10 min read
FEATURECardiac Stem Cells Results from the first round of controlled human stem cell trials for heart disease are in. What have we learned?BY KENNETH CHIENA bleedng heart, Dicentra formosa © ROBERT ESSEL NYC/CORBISFor patients with chronic degenerative diseases such as heart failure, regenerative medicine holds great promise. It is this compelling need that has created a sense of urgency, leading t

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