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Molecular Biology
The Scientist Staff | Mar 1, 1992 | 2 min read
D.W. Nebert, D.R. Nelson, M.J. Coon, R.W. Estabrook, et al., "The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature," DNA and Cell Biology, 10:1-14, 1991. Daniel W. Nebert (University of Cincinnati Medical Center): "This review is the third in a series of comprehensive, up- to-date compilations of data about members of the large cytochrome P450 gene superfamily. It serves to organize a large--and growing--body of sequencing and mapping data on 154 P450 genes
An Overview of High Throughput Screening
An Overview of High Throughput Screening
Tanvir Khan, PhD | Jan 2, 2024 | 5 min read
High throughput screening (HTS) relies on liquid handling devices, robotics, plate readers, and data processing software to automatically test a large number of biological, genetic, chemical, or pharmacological samples. 
Cartoon of scientist deciding whether to go down the path of well-studied genes or that of the neglected genes. 
Stepping Into the Unknome
Danielle Gerhard, PhD | Mar 8, 2024 | 5 min read
A database of neglected genes may help unlock the mysteries hiding in the overlooked regions of the proteome.
a spiny mouse sits on a piece of wood holding a small morsel to its mouth
Spiny Mice Appear to Regenerate Damaged Kidneys
Dan Robitzski | Nov 3, 2021 | 5 min read
The mice, already known to regenerate skin, seem to avoid the tissue scarring that leads to organ failure in other animals.
immune cells t cell natural kill cell cardiac stem cell ipsc
Gene Editing Makes Cells Evade Immune Attack In Vitro
Emma Yasinski | Dec 12, 2019 | 3 min read
To advance the possibility of off-the-shelf cardiac cell therapies, scientists devise an engineered cardiac stem cell that avoids stimulating a detrimental immune attack.
Molecular Structures Provide Insights Into Larger Questions In Biology
Neeraja Sankaran | Sep 4, 1994 | 6 min read
Editor's Note: This is the second part of a two-part series on the field of structural biology. Part 1, presented in the Aug. 22, 1994, issue of The Scientist (page 14), discussed the evolution of this booming discipline. This article focuses on structural biology's key areas of basic and applied research and looks ahead to its future. Following are some of the professional organizations whose memberships include structural biolo
Molecular Structures Provide Insights Into Larger Questions In Biology
Neeraja Sankaran | Sep 4, 1994 | 6 min read
Editor's Note: This is the second part of a two-part series on the field of structural biology. Part 1, presented in the Aug. 22, 1994, issue of The Scientist (page 14), discussed the evolution of this booming discipline. This article focuses on structural biology's key areas of basic and applied research and looks ahead to its future. Following are some of the professional organizations whose memberships include structural biolo
3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Whither Cell Biology?
Richard Hynes | Dec 10, 2000 | 6 min read
Illustration: A. Canamucio Cell biology has become the third overlapping core discipline of modern biology, along with biochemistry and genetics. Progress over the century--since E.B. Wilson's classic book1 elegantly framed many of the questions of cell biology--has relied on advances in technology and yielded fascinating insights into the ways that cells work. We now have an unprecedented understanding of the structure, organization, and functions of cells. As the number of completed ge

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