Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Rather than introducing small chunks of DNA as other viruses do, some giant viruses can contribute more than 1 million base pairs to a host’s genome, broadening the ways in which viruses may shape eukaryote evolution.
Most of the human induced pluripotent stem cells stored at major cell line repositories and used in research harbor thousands of DNA errors, a study finds, highlighting the need for improved quality control measures.