Early exposure to microbes shapes the mammalian immune system by subduing inflammatory T cells.
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Replacing immune cells in a mouse model of Rett syndrome, a developmental brain disorder, improved symptoms, suggesting a new target for treatment.
A new method for transplanting immunologically mismatched organs may remove the need for life-long immunosuppressive drugs to prevent rejection.
Exercise causes short-term changes in DNA methylation and gene expression in muscle tissue that may have implications for type 2 diabetes.
A lot changes in a child’s body over the course of development, and not all changes occur linearly: gene expression can fluctuate, and organs can perform different functions on the way to their final purpose in the body. Here are some of the key deve
Vitamin D has a variety of actions in the body. It binds to the vitamin D receptor (VDR), which then binds to the retinoid X receptor (RXR) and activates the expression of numerous genes. Through this mechanism, vitamin D promotes calcium absorption
When children need medications, getting the dosing and method of administration right is like trying to hit a moving target with an untried weapon.
Prevention trials for vitamins and supplements are notoriously difficult, but some researchers aren’t giving up on finding proof that vitamin D helps ward off disease.
Immune cells in skin provide powerful protection against infection, suggesting new routes for vaccination.
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