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image: CRISPR Screen Detects Functional Gene Regulation

CRISPR Screen Detects Functional Gene Regulation

By | April 3, 2017

A CRISPR-Cas9–based method probes the regulatory roles of noncoding DNA sequences.

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image: Cancer Genomes

Cancer Genomes

By | April 1, 2017

April Scientist to Watch Angela Brooks of the University of California, Santa Cruz, discusses her search to find vulnerabilities buried within the genomes of cancer cells.

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image: Angela Brooks: Splicing Specialist

Angela Brooks: Splicing Specialist

By | April 1, 2017

At the University of California, Santa Cruz, the researcher combs the cancer genome, looking for weaknesses.

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image: Book Excerpt from <em>The Politics of Cancer</em>

Book Excerpt from The Politics of Cancer

By | April 1, 2017

In Chapter 2, “Identifying the Culprits,” author Wendy Whitman Cobb describes how small-government, anti-regulation conservatism can hinder the fight against cancer.

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image: Gel Scaffolds for Delivery of Immunotherapies

Gel Scaffolds for Delivery of Immunotherapies

By | April 1, 2017

Using biocompatible polymers to carry cancer immune therapies directly to the tumor

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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image: Record-Setting Corn Grows 45 Feet Tall

Record-Setting Corn Grows 45 Feet Tall

By | April 1, 2017

A plant breeder succeeds in growing a huge maize plant thanks to a known mutation and a few environmental tricks.

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image: Neoantigens Enable Personalized Cancer Immunotherapy

Neoantigens Enable Personalized Cancer Immunotherapy

By | April 1, 2017

Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.

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image: Infographic: Antibody Cancer Therapy

Infographic: Antibody Cancer Therapy

By | April 1, 2017

An experimental technique removes T cells that aid in vitro tumor growth.

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image: Infographic: Targeting Cancer Antigens

Infographic: Targeting Cancer Antigens

By | April 1, 2017

Neoantigens may serve as valuable targets for new immunotherapies.

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