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tag felisa wolfe simon cell molecular biology neuroscience

Arsenic-based life debate continues
Jessica P. Johnson | Jun 2, 2011 | 3 min read
More than a dozen researchers voice their concerns about a 2010 paper that claims bacteria can use arsenic in place of phosphorus in its DNA and other biomolecules, such as proteins.
Arsenic-based life debate continues
Jessica P. Johnson | Jun 1, 2011 | 3 min read
More than a dozen researchers voice their concerns about a 2010 paper that claims bacteria can use arsenic in place of phosphorus in its DNA and other biomolecules
Setting the Record Straight
Daniel Cossins | Oct 1, 2014 | 10+ min read
Scientists are taking to social media to challenge weak research, share replication attempts in real time, and counteract hype. Will this online discourse enrich the scientific process?
Death Watch II: Caspases and Apoptosis
Jorge Cortese | Jun 24, 2001 | 10 min read
Caspase Related Reagents Courtesy of Bingren Hu, Queen's Medical Center, Hawaii. Provided by Cell Signaling TechnologyConfocal micrograph of double immunostaining for cleaved caspase-3 (green) and propidium iodide (red) in newborn rat brain tissue. This section shows control and transient cerebral ischemia. Editor's Note: This is the second article in our two-part series on cell death. The first part: J. Cortese, "Death watch I: Cytotoxicity detection," The Scientist, 15[5]:26, March 5, 2001.
The Tiniest of Life's Rafts
Jill Adams | Oct 10, 2004 | 6 min read
LIPID RAFTS INSIDE AND OUT:© 2002 AAASIn the outer leaflet (A), sphingolipids and cholesterol form less fluid microdomains (B) called lipid rafts, which are enriched for GPI-proteins. Microdomains may contain more rigid subdomains (C) enriched for the sphingolipid ganglioside GM1. The membrane inner leaflet contains microdomains (D) with unknown lipid composition enriched for prenylated proteins. In contrast, caveolin and proteins carrying the two saturated fatty acyl chains become concentr

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