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tag felisa wolfe simon cell molecular biology genetics genomics

Epigenetics: Genome, Meet Your Environment
Leslie Pray | Jul 4, 2004 | 10+ min read
©Mehau Kulyk/Photo Researchers, IncToward the end of World War II, a German-imposed food embargo in western Holland – a densely populated area already suffering from scarce food supplies, ruined agricultural lands, and the onset of an unusually harsh winter – led to the death by starvation of some 30,000 people. Detailed birth records collected during that so-called Dutch Hunger Winter have provided scientists with useful data for analyzing the long-term health effects of prenat
Cool Cloning
Karen Hopkin | Jul 1, 2008 | 7 min read
Lynn Cooley figured she'd study sea creatures, then decided to revolutionize genetics instead.
Yeast: An Attractive, Yet Simple Model
Gregory Smutzer | Sep 16, 2001 | 9 min read
Yeast possesses many characteristics that make it especially useful as a model system in the laboratory, including an entirely sequenced genome. Recently, a number of researchers published studies detailing the transition from genome sequencing to functional genomics. Notably, these scientists have developed new high-throughput approaches to the characterization of large numbers of yeast genes. In aggregate, these studies make yeast one of the most well-characterized eukaryotic organisms known.
Arsenic-based life debate continues
Jessica P. Johnson | Jun 2, 2011 | 3 min read
More than a dozen researchers voice their concerns about a 2010 paper that claims bacteria can use arsenic in place of phosphorus in its DNA and other biomolecules, such as proteins.
Arsenic-based life debate continues
Jessica P. Johnson | Jun 1, 2011 | 3 min read
More than a dozen researchers voice their concerns about a 2010 paper that claims bacteria can use arsenic in place of phosphorus in its DNA and other biomolecules
Setting the Record Straight
Daniel Cossins | Oct 1, 2014 | 10+ min read
Scientists are taking to social media to challenge weak research, share replication attempts in real time, and counteract hype. Will this online discourse enrich the scientific process?
The Orange and the Circus Tent
Ari Helenius | Oct 1, 2008 | 9 min read
The Orange and the Circus Tent Illustrations by Grady McFerrin What viruses teach us about the workings of mammalian cells. By Ari Helenius Article Extras 1 In those days, my interest was largely biochemical, particularly in the properties of membrane proteins, although I did also spend a lot of time trying to take the virus apart to its individual components, in an attempt to recreate the infectious particle from scratch. Needless to sa
Top 10 Innovations 2016
The Scientist | Dec 1, 2016 | 10+ min read
This year’s list of winners celebrates both large leaps and small (but important) steps in life science technology.
The Scientist Top Innovations of 2008
Alison McCook | Dec 1, 2008 | 10+ min read
The Scientist Top Innovations of 2008 For the first time, we laud the ten most outstanding new products to hit the life science market. The life sciences move fast. Across the globe, companies are constantly churning out new products that they say will make your research smarter. For six years, we've ranked the vendors of life science equipment in our Life Science Industry Awards. Now, to recognize winning combinations of invention, vision and
A Thousand Points of Light
Bob Sinclair | Oct 15, 2000 | 10+ min read
Not so long ago, researchers had somewhat limited choices for locating and following a particular piece of DNA. A probe could be labeled using radioactivity, by kinasing an end or nick-translating the whole piece. A fragment of interest could be visualized (along with all other DNA and RNA species in the preparation) using ethidium bromide. With sufficient skill and patience an investigator could obtain from these rather crude techniques fairly impressive information, such as the precise 5' end

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