The largest study of its kind identifies single nucleotide polymorphisms with disparate effects on men’s and women’s susceptibility to conditions such as bipolar disorder and schizophrenia.

The gene, aquaporin-4, is critical in rodents for the cerebrospinal fluid bath the brain gets during sleep. It’s now also tied to slow wave electrical activity during deep sleep in people.

No two neurons are alike. What does that mean for brain function?

Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.

The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.

From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.

By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo

To help create better conservation and management plans, researchers are measuring how marine organisms move between habitats and populations.

From a mass photometer to improved breath biopsy probes, these new products are poised for scientific success.

CRISPR patent ruling appealed; CRISPR-based nucleic acid test; an experimental gene therapy for Duchenne muscular dystrophy and a cell-based protocol for Parkinson’s disease show promise in mice