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tag single nucleotide polymorphism immunology genetics genomics

Single Nucleotide Polymorphisms: Big Pharma Hedges its Bets
Eugene Russo | Jul 18, 1999 | 7 min read
SNP CENTRAL: A genetics researcher takes to the bench at the Wellcome Trust's Sanger Centre in Cambridge, England. The sequencing center and its London sponsor provided key leadership in the SNP Consortium, a public-private venture to find and map 300,000 single nucleotide polymorphisms. The Wellcome Trust helped entice 10 pharmaceutical firms to join the consortium by putting up $14 million of the project's estimated $45 million price tag. The Sanger Centre will provide much of the radiation h
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Whole-Genome Genotyping on Microarrays
Charles Choi | Jul 3, 2005 | 1 min read
To map most of the genetic variation in the human genome, scientists need to look at several hundred thousand single nucleotide polymorphisms (SNPs) per individual.
GWAS, psychotic disorder, mood disorder, Q&A, bipolar disorder, schizophrenia, depression, sex differences
Genetic Variants Tied to Sex Differences in Psychiatric Disorders
Amanda Heidt | Mar 31, 2021 | 5 min read
The largest study of its kind identifies single nucleotide polymorphisms with disparate effects on men’s and women’s susceptibility to conditions such as bipolar disorder and schizophrenia.
Illustration showing mouse being injected with AAV mixture
Infographic: Taking AAV screening to the next level
Mariella Bodemeier Loayza Careaga, PhD | Mar 8, 2024 | 2 min read
DNA barcodes in AAV vectors technology simplified AAV screening.
front view of a green grasshopper with a white and orange face.
Why Do Male Organisms Exist?
Hannah Thomasy, PhD | Mar 1, 2024 | 2 min read
Some species of lizards, grasshoppers, and crustaceans have adopted a ladies-only lifestyle.
DASH-ing Through the Genome
Grace Athas | Oct 24, 1999 | 2 min read
Hybaid's Dynamic Allele Specific Hybridization system Understanding the relationship between genetic variations at the nucleotide sequence level and human disease will profoundly change prevention and treatment methods in the next decade. The DNA sequence information produced through the Human Genome Project will reveal thousands of variations at single nucleotides, termed single nucleotide polymorphisms (SNPs). Such sequence variations in DNA may disrupt gene function and be causally associated
Key Mental Illness Genes Found
Bob Grant | Mar 4, 2013 | 1 min read
A large genome-wide study has identified four single-nucleotide polymorphisms shared between five major psychiatric disorders.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
A fossilized mammoth tusk sitting in a grassy field during sunset 
Woolly Mammoth Genomes Reveal Genetic Adaptations to Cold
Hannah Thomasy, PhD | Dec 12, 2022 | 2 min read
Researchers identified mutations in genes that may be involved in fat regulation, fur growth, and morphology.

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