ADVERTISEMENT

404

Not Found

Is this what you were looking for?

tag single nucleotide polymorphism disease medicine genetics genomics

Single Nucleotide Polymorphisms: Big Pharma Hedges its Bets
Eugene Russo | Jul 18, 1999 | 7 min read
SNP CENTRAL: A genetics researcher takes to the bench at the Wellcome Trust's Sanger Centre in Cambridge, England. The sequencing center and its London sponsor provided key leadership in the SNP Consortium, a public-private venture to find and map 300,000 single nucleotide polymorphisms. The Wellcome Trust helped entice 10 pharmaceutical firms to join the consortium by putting up $14 million of the project's estimated $45 million price tag. The Sanger Centre will provide much of the radiation h
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Two sets of identical twin children sitting
Identical Twins Carry Distinctive Epigenetic Marks: Study
Chloe Tenn | Sep 30, 2021 | 2 min read
Researchers found more than 800 sites in the genome where the twins bore the same chemical tags.
GWAS, psychotic disorder, mood disorder, Q&A, bipolar disorder, schizophrenia, depression, sex differences
Genetic Variants Tied to Sex Differences in Psychiatric Disorders
Amanda Heidt | Mar 31, 2021 | 5 min read
The largest study of its kind identifies single nucleotide polymorphisms with disparate effects on men’s and women’s susceptibility to conditions such as bipolar disorder and schizophrenia.
DASH-ing Through the Genome
Grace Athas | Oct 24, 1999 | 2 min read
Hybaid's Dynamic Allele Specific Hybridization system Understanding the relationship between genetic variations at the nucleotide sequence level and human disease will profoundly change prevention and treatment methods in the next decade. The DNA sequence information produced through the Human Genome Project will reveal thousands of variations at single nucleotides, termed single nucleotide polymorphisms (SNPs). Such sequence variations in DNA may disrupt gene function and be causally associated
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Snip-SNPs in the worm genome
Jonathan Weitzman(jonathanweitzman@hotmail.com) | Jun 5, 2001 | 1 min read
SNPs (single nucleotide polymorphisms) are valuable markers for mapping mutations and human disease-related genes. In the June issue of Nature Genetics, Wicks et al. describe a SNP-based strategy for rapid mapping in the C. elegans genome (Nature Genetics 2001, 28:160-164). They sequenced the entire genome of the CB4856 Hawaiian worm isolate and compared it with the standard laboratory wild type strain (Bristol N2). This alignment identified 6,222 potential polymorphisms, more than half of which
A gloved hand holds a tweezer and pulls a section of DNA away from a double helix
First Person Dosed in Novel Gene Editing Clinical Trial
Amanda Heidt | Jul 12, 2022 | 4 min read
The biotech company Verve Therapeutics launched the study with the aim of using base editing to treat a genetic condition that causes high cholesterol and increases a person's risk of developing cardiovascular disease.
ABI Poised to Break the SNP Genotyping Speed Barrier?
Deborah Stull | Mar 23, 2003 | 2 min read
Courtesy of Applied Biosystems Single nucleotide polymorphisms--variations at specific nucleotide positions in the genome sequences of two individuals--are perhaps the most common form of genetic diversity; it is estimated that 3-10 million SNPs are present in the human genome. Researchers use these markers to map disease genes, and in the burgeoning field of pharmacogenomics (personalized medicine). Such research necessarily requires the ability to genotype on a grand scale, but until recent

Run a Search

ADVERTISEMENT