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tag single nucleotide polymorphism evolution

Single Nucleotide Polymorphisms: Big Pharma Hedges its Bets
Eugene Russo | Jul 18, 1999 | 7 min read
SNP CENTRAL: A genetics researcher takes to the bench at the Wellcome Trust's Sanger Centre in Cambridge, England. The sequencing center and its London sponsor provided key leadership in the SNP Consortium, a public-private venture to find and map 300,000 single nucleotide polymorphisms. The Wellcome Trust helped entice 10 pharmaceutical firms to join the consortium by putting up $14 million of the project's estimated $45 million price tag. The Sanger Centre will provide much of the radiation h
front view of a green grasshopper with a white and orange face.
Why Do Male Organisms Exist?
Hannah Thomasy, PhD | Mar 1, 2024 | 2 min read
Some species of lizards, grasshoppers, and crustaceans have adopted a ladies-only lifestyle.
SNPs as Windows on Evolution
Ricki Lewis | Jan 6, 2002 | 7 min read
Single nucleotide polymorphisms--variants in DNA sequences better known as SNPs and pronounced snips--provide a shortcut to comparing genes and genomes within and among species. The need to study SNPs has spawned a number of companies aimed at matching SNP patterns to disease risks. A few other organizations, however, are taking a broader view: mining SNPs for clues to human diversity and evolution. Association studies that correlate SNP patterns to disease risks are straightforward. Clues to
A fossilized mammoth tusk sitting in a grassy field during sunset 
Woolly Mammoth Genomes Reveal Genetic Adaptations to Cold
Hannah Thomasy, PhD | Dec 12, 2022 | 2 min read
Researchers identified mutations in genes that may be involved in fat regulation, fur growth, and morphology.
Universal Array Makes Genotyping a SNaP
Marilee Ogren | Jul 21, 2002 | 2 min read
Rapidly evolving genomic technologies have spawned the Tm/Luminex Universal Array Platform, capable of reading 10,000 single nucleotide polymorphisms (SNPs) per hour. Distributed by Luminex of Austin, Texas, the system is the product of a partnership between Luminex and Tm Bioscience of Toronto. Luminex pioneered multiplexed, bead-based genotyping with LabMAP™ (now called xMAP™).1 Tm Biosciences recently developed the Universal Array, an arbitrary set of nucleotide sequences for an
A tasmanian devil with its nose in the air
Deadly Facial Tumors Spur Tasmanian Devil Evolution: Study
Christie Wilcox, PhD | Jun 16, 2021 | 6 min read
The largest study to date of the animals’ genetics provides robust evidence that they are adapting to survive a highly lethal, contagious cancer scientists feared would cause their extinction.
Fraction of SNPs Can Affect Fitness
Kerry Grens | Jan 21, 2015 | 1 min read
A point mutation analysis of the entire human genome finds that alterations to as many as 7.5 percent of nucleotides may have contributed to humans’ evolutionary split from chimpanzees.
Epithelial cells and fungal spores are marked with fluorescent dyes. Cells have an irregular shape and are shown in green and blue colors. Spores are spherical in shape and are labeled green if they are surrounded by p11 protein. A protein in mature phagosomes is labeled violet.
Fungal Spores Hijack a Host Protein to Escape Death
Mariella Bodemeier Loayza Careaga, PhD | Jun 20, 2023 | 3 min read
Uncovering the components used by Aspergillus fumigatus to avoid intracellular destruction broadens our understanding of the mold’s pathogenesis. 
Photo of a North American caribou (Rangifer tarandus) in Jasper National Park in Canada
Dozens of Genes Tied to Caribou’s Seasonal Migration
Maddie Bender | May 2, 2022 | 2 min read
Researchers tracked the movements of endangered caribou and sequenced a portion of their genomes to determine which genes may influence migratory behavior.
Migrations influenced immune evolution
Melissa Lee Phillips | Oct 4, 2007 | 3 min read
Human innate immunity differs between Africans and others, perhaps due to different infectious environments

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