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tag viral vectors microbiology disease medicine

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
Going Viral
Breeann Kirby and Jeremy J. Barr | Sep 1, 2013 | 10+ min read
From therapeutics to gene transfer, bacteriophages offer a sustainable and powerful method of controlling microbes.
A watercolor of a baby in a heart-shaped womb
Sex of Fetus Affects Immune Response to COVID-19 During Pregnancy
Amanda Heidt | Oct 20, 2021 | 3 min read
Male placentas produce more proinflammatory molecules than female placentas, while people carrying male fetuses produce fewer antibodies in response to infection, a study finds.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
illustration of a coronavirus and antibodies
When the Immune Response Makes COVID-19 Worse
Alejandra Manjarrez, PhD | Sep 27, 2021 | 8 min read
If the immune system makes mistakes—reacting late or getting the target wrong—it can amplify the damage wrought by SARS-CoV-2.
Illustration of a person sick next to a calendar indicating they've had covid for a long time
Mechanisms of Long COVID Remain Unknown but Data Are Rolling In
Sruthi S. Balakrishnan | Sep 1, 2021 | 10+ min read
A year and a half into the pandemic, the long-term effects of SARS-CoV-2 infection are garnering more research attention as millions of long COVID patients emerge.
johnson & johnson johnson&johnson j&j janssen covid-19 vaccine vaccination pandemic adenovirus vector blood clot side effect cerebral venous sinus thrombosis CVST sars-cov-2 coronavirus pandemic astrazeneca
US Health Authorities Ask for Pause in J&J COVID-19 Vaccination
Kerry Grens | Apr 13, 2021 | 2 min read
The FDA and CDC are investigating a handful of reports of blood clots that occurred several days after people received the one-and-done shot.
False-colored micrograph of Mycobacterium tuberculosis
Tuberculosis: The Forgotten Pandemic
Anthony King | Jul 1, 2021 | 10+ min read
This month marks the 100-year anniversary of BCG, still the only approved vaccine against the lethal pathogen. But there are new vaccines for this wily foe on the horizon.

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