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tag viral vectors disease medicine
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
Curiosity and Compassion Fuel Rare Disease Research
The Scientist
Staff
| Jan 1, 2024
| 1 min read
Lauren Drouin shares how personal connections and scientific curiosities drive her work on gene therapy viral vectors.
A Journey Into the Brain
Danielle Gerhard, PhD
| Mar 22, 2024
| 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Turning on the Bat Signal
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Which Gene Therapy Delivery Vector Will Emerge Victorious?
Danielle Gerhard, PhD
| Oct 2, 2023
| 2 min read
In the race to deliver successful gene therapies, frontrunner AAVs come head to head with underdog lipid nanoparticles.
Insertional Mutagenesis from a Viral Vector
Josh Roberts(jroberts@the-scientist.com)
| May 8, 2005
| 6 min read
Integrated viral sequences can dysregulate genes.
Newly Developed mRNA Vaccine Protects Against Lyme Disease
Charlene Lancaster, PhD
| Nov 13, 2023
| 5 min read
Leveraging the same mRNA platform used for COVID-19 vaccines, researchers generated a vaccine that prevents mice from acquiring Lyme disease.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD
| Mar 15, 2024
| 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
Thwarting AAV-Neutralizing Antibodies Could Improve Gene Therapy
Emma Yasinski
| Sep 25, 2020
| 5 min read
Adeno-associated viral vectors can deliver gene therapies, but AAV-neutralizing antibodies might prevent the medicines from working.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
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