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tag colony pickers developmental biology

Automated Colony Pickers Evolve
Helen Dell(hdell@the-scientist.com) | Jul 3, 2005 | 6 min read
Everyone knows that the first genome sequencing projects took years of work and represent the combined product of tens of thousands of individual fragments.
colonies of mold growing on a Petri dish
Fungi Squeezed Through Microchannels Offer Clues to Cell Growth
Catherine Offord | Jun 1, 2021 | 3 min read
A study finds that fast-growing species are stymied by narrow gaps, while slower-growing species can pass through and continue extending.
Notebook
Eugene Russo | Dec 5, 1999 | 7 min read
Contents Pivotal pump Leptin limbo Clue to obesity Biotech Web site Helping hand Mapping malaria Notebook Pictured above are pigmented bacterial colonies of Deinococcus radiodurans, the most radiation-resistant organism currently known. DEINO-MITE CLEANUP In 1956, investigators discovered a potentially invaluable cleanup tool in an unlikely place. A hardy bacterium called Deinococcus radiodurans unexpectedly thrived in samples of canned meat thought to be sterilized by gamma radiation. The b
A scanning electron micrograph of a coculture of E. coli and Acinetobacter baylyi. Nanotubes can be seen extending from the E. coli.
What’s the Deal with Bacterial Nanotubes?
Sruthi S. Balakrishnan | Jun 1, 2021 | 10+ min read
Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?
Beyond Film: Laboratory Imagers
Jorge Cortese | Apr 1, 2002 | 9 min read
Years ago, researchers had only one data-imaging option: autoradiography. These scientists tagged samples—whether nucleic acid, protein, cell, or tissue—with radioactive labels, and captured images on film. Safety concerns, convenience, and sensitivity, spurred the development of alternative techniques, and today, researchers can choose from a range of options, including fluorescence, chemifluorescence, and chemiluminescence, in addition to autoradiography. Fluorescence occurs when
Array of Options
Jorge Cortese | May 28, 2000 | 10 min read
Instrumentation for Microarray Production and Analysis - Part 1 Instrumentation for Microarray Production and Analysis - Part 2 Nanogen's NanoChip™ Cartridge Today's molecular biology era can be defined by the dictum, "So many genes, so little time," and technologies for gathering genetic information are gaining speed. DNA microarrays are one of the most promising answers to that cry. DNA microarrays are glass microslides or nylon membranes containing DNA samples (genomic DNA, cDNA,
The Genetics of Society
Claire Asher and Seirian Sumner | Jan 1, 2015 | 10 min read
Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.
Stem Cell Know-How
Aileen Constans | Sep 1, 2002 | 7 min read
Image: Courtesy of Gwenn-AEL Dnaet ©2002 National Academy of Sciences STEM CELL XENOGRAFT: Identification of human hepatocytes in livers from immune-deficient mice transplanted with human adult hematopoietic stem cells. Photomicrographs of NOD/SCID mouse liver sections from mice transplanted with purified human Lin-CD38-CD34-C1qRp+ cells isolated from umbilical cord blood, harvested 8-10 weeks post-transplant. Tissue sections were stained for HSA (hepatocyte-specific antigen) or c-met
Unraveling Protein-Protein Interactions
Leslie Pray | Jan 26, 2003 | 8 min read
Courtesy of Adrian Arakaki THERE'S GOLD IN THEM THERE COMPLEXES: Digging up protein-protein interactions with MULTIPROSPECTOR. Using a computer instead of a pipette, Jeffrey Skolnick contemplates the subtle forces that bring proteins together. His first computational forays helped decipher the quaternary structure of proteins--the interactions between subunits in molecules such as tropomyosin. Now Skolnick, executive director of the Buffalo Center of Excellence in Bioinformatics, Buffalo
Pursuing Proteomes
Deborah Wilkinson | Jun 11, 2000 | 9 min read
Bio-Rad's PROTEAN® IEF System provides 2-D electrophoretic separation as part of the ProteomeWorks System Australian postdoctoral fellow Marc Wilkins coined the term "proteome" in the mid-'90s, referring to the total set of proteins expressed in a given cell at a given time. The term took hold, and a new scientific discipline was born. In proteomic studies, all the proteins from a given cell, organelle, or tissue are analyzed simultaneously with respect to properties such as expression leve

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