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image: What Causes Alzheimer’s?

What Causes Alzheimer’s?

By | September 1, 2011

Researchers and pharma companies have tried to attack this disease by reducing amyloid plaques, but inflammation may be the real culprit.

39 Comments

image: Seeing Through Mice

Seeing Through Mice

By | September 1, 2011

A new technique for turning mouse fetuses transparent offers a literal window into the brain.

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image: Lost in Space

Lost in Space

By | September 1, 2011

Looking for a more realistic way to study memory, we turned to place cells­­—­a network of cells that record a rat’s memory of an environment. Each place cell would fire only when the rat was in one particular location in space, creating a map as the

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image: The Seat of Memory

The Seat of Memory

By | September 1, 2011

Early on, researchers had learned that the hippocampus was the structure in the brain where long-term memories were created and stored, but it was not known whether the different cell types within this structure might be more or less susceptible to t

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image: The Cytokine Cycle

The Cytokine Cycle

By | September 1, 2011

The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—­­from traumatic brain injury, to epilepsy, infection, or genetic predisposition—­can activate brain immune cells—­­

12 Comments

image: Rats Don't Map Altitude

Rats Don't Map Altitude

By | August 8, 2011

Rat neurons only weakly respond as the animals climbed upwards, suggesting the brain's map of the environment doesn't account for altitude.

9 Comments

Contributors

July 1, 2011

Meet some of the people featured in the July 2011 issue of The Scientist.

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image: Foresight

Foresight

By | July 1, 2011

Studying the earliest events in visual development, Carla Shatz has learned the importance of looking at one’s data with open eyes—and an open mind.

12 Comments

image: Monkey mind control

Monkey mind control

By | May 27, 2011

Even while remaining motionless, macaques are able to increase the activity of a particular brain region, improving their concentration and search abilities

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image: Face to Face with the Emotional Brain

Face to Face with the Emotional Brain

By | February 1, 2011

Amygdala responses to the facial signals of others predict both normal and abnormal emotional states. An understanding of the brain chemistry underlying these responses will lead to new strategies for treating and predicting psychopathology.

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