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image: Behavior Brief

Behavior Brief

By | September 13, 2011

A round-up of recent discoveries in behavior research

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image: Secrets of Aging

Secrets of Aging

By | September 1, 2011

What does a normally aging brain look like? Are diseases of aging such as Alzheimer’s inevitable?

78 Comments

image: What Causes Alzheimer’s?

What Causes Alzheimer’s?

By | September 1, 2011

Researchers and pharma companies have tried to attack this disease by reducing amyloid plaques, but inflammation may be the real culprit.

39 Comments

image: Seeing Through Mice

Seeing Through Mice

By | September 1, 2011

A new technique for turning mouse fetuses transparent offers a literal window into the brain.

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image: Lost in Space

Lost in Space

By | September 1, 2011

Looking for a more realistic way to study memory, we turned to place cells­­—­a network of cells that record a rat’s memory of an environment. 

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image: The Seat of Memory

The Seat of Memory

By | September 1, 2011

Early on, researchers had learned that the hippocampus was the structure in the brain where long-term memories were created and stored, but it was not known whether the different cell types within this structure might be more or less susceptible to the aging process.

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image: The Cytokine Cycle

The Cytokine Cycle

By | September 1, 2011

The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—­­from traumatic brain injury, to epilepsy, infection, or genetic predisposition—­can activate brain immune cells—microglia and astrocytes-- promoting them to produce IL-1 and S100 inflammatory cytokines.

12 Comments

image: Rats Don't Map Altitude

Rats Don't Map Altitude

By | August 8, 2011

Rat neurons only weakly respond as the animals climbed upwards, suggesting the brain's map of the environment doesn't account for altitude.

9 Comments

Contributors

July 1, 2011

Meet some of the people featured in the July 2011 issue of The Scientist.

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image: Foresight

Foresight

By | July 1, 2011

Studying the earliest events in visual development, Carla Shatz has learned the importance of looking at one’s data with open eyes—and an open mind.

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