So-called mossy fiber synapses in the hippocampus can meter the amount of neurotransmitter they receive by sending glutamate against the usual direction of synaptic flow.
In an unexpected twist in neuroscience dogma, the cells on the receiving end of neurotransmission appear to be able to release glutamate to regulate the transmitting cell’s activity.
Fred H. Gage, Tracy A. Bedrosian, and Sara B. Linker | Oct 31, 2017 | 2 min read
Recent advances in single-cell omics and other techniques are revealing variation at genomic, epigenomic, transcriptomic, and posttranscriptomic levels.
Male mice exposed to females, their urine, or a chemical in their urine lost sensory neurons in their vomeronasal organs that respond to that chemical.
The brain’s ability to make new neural connections can be restored in mice by blocking a protein that normally acts as a natural brake on neuroplasticity.
Converting sights to sounds reveals that the brains of congenitally blind people respond similarly to various objects as those of subjects who can see.