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tag neurodegenerative diseases cell molecular biology developmental biology culture

Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Biology’s New Supermodel
Megan Scudellari | Jul 20, 2011 | 5 min read
Induced pluripotent stem cells are biology’s hottest new tool for understanding human disease.
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021 | 10+ min read
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
Leveraging Stem Cells to Create Better Disease Models
Leveraging Stem Cells to Create Better Disease Models
The Scientist | May 29, 2023 | 2 min read
Clive Svendsen, Meritxell Huch, Ameen Salahudeen, and Maksim Plikus will discuss the latest advances in using patient-derived stem cells to create more accurate disease models.
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker, PhD | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.
The figure shows two waves made of DNA double helixes representing gene expression changes in the malaria parasite and its human host. These changes reveal a synchronization between parasite and host.
Malaria Parasites Sync with Hosts’ Molecular Rhythms
Mariella Bodemeier Loayza Careaga, PhD | Sep 1, 2023 | 2 min read
Evidence of malaria parasites aligning with their human hosts may pave the way for new antimalarial agents.
Researchers CHOOSE Organoids to Investigate Neurodevelopment
Deanna MacNeil, PhD | Jan 29, 2024 | 4 min read
A 3D variation of pooled CRISPR screens could connect the dots between autism spectrum disorder genetics and cell fate pathways in the developing brain.
A nude (hairless) mouse, typically used in biomedical and drug discovery research methods that rely on immunodeficient mouse strains.
Brush Up: Humanized Mice: More than the Sum of Their Parts
Deanna MacNeil, PhD | Aug 31, 2022 | 5 min read
Scientists study human health in vivo with modified mice that molecularly mimic human biology.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.

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