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tag neurodegenerative diseases cell molecular biology ecology disease medicine

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021 | 10+ min read
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
Journal club logo on purple background
The Scientist's Journal Club: Transcriptomics
The Scientist | Sep 20, 2023 | 2 min read
Scientists discuss their latest findings on immune cell dynamics, neurodegenerative disease risk factors, and rare cell types obtained from bulk and single cell RNA sequencing experiments.
Are All Neurodegenerative Diseases Made Equal?
The Scientist | Jan 2, 2018 | 2 min read
The Scientist is bringing together a panel of experts to share their research, discuss current therapeutic approaches, and to offer their insights.
Innovative Drug Targets for Neurodegenerative Disease
PhoreMost LTD | Oct 17, 2016 | 2 min read
PhoreMost Ltd and University of Cambridge collaborate to identify innovative drug targets for neurodegenerative disease
3D illustration of damaged myelin sheath seen in demyelinating diseases such as multiple sclerosis.
Tracking Down Innate Immune Cells in Multiple Sclerosis
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 5 min read
A novel PET tracer targeting a receptor in myeloid cells can help monitor disease progression in a mouse model of multiple sclerosis.
Tiled blue-gray MRI readouts of a human brain.
Cancer Tied to Reduced Risk of Alzheimer’s Disease
Dan Robitzski | Apr 14, 2022 | 7 min read
Observational evidence for the connection is solidifying, and some clues are emerging about the mechanisms that may explain it.
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker, PhD | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.
Huntington's Disease
The Scientist Staff | Sep 12, 1999 | 3 min read
Edited by: Paul Smaglik M. DiFiglia, E. Sapp, K.O. Chase, S.W. Davies, G.P. Bates, J.P. Vonsattel, N. Aronin, "Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain," Science, 277:1990-3, 1997. (Cited in more than 200 papers since publication) Neil Aronin Comments by Neil Aronin, professor of medicine and cell biology, Massachusetts Medical Center, Worcester, Mass. The pathogenic connection between huntingtin the protein and Huntington's the disease
Biology’s New Supermodel
Megan Scudellari | Jul 20, 2011 | 5 min read
Induced pluripotent stem cells are biology’s hottest new tool for understanding human disease.

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