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tag neurodegenerative diseases evolution ecology

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
a black abalone on a rock
Genome Spotlight: Black Abalone (Haliotis cracherodii)
Christie Wilcox, PhD | Jun 23, 2022 | 3 min read
The researchers who constructed the first reference genome for this critically endangered mollusk say it will assist restoration efforts.
Peter Tyack: Marine Mammal Communications
Anna Azvolinsky | Jul 1, 2016 | 9 min read
The University of St. Andrews behavioral ecologist studies the social structures and behaviors of whales and dolphins, recording and analyzing their acoustic communications.
The Brain Inside Out: Mapping the Nervous System Wiring
The Brain Inside Out: Mapping the Nervous System's Wiring
The Scientist | Jan 25, 2022 | 1 min read
An expert panel will describe their efforts to chart billions of neuronal connections and discuss how this data provides unparalleled insight into neuronal cell biology, signal processing, and behavior.
Quickening the Diagnosis of Mad Cow Disease
Laura Defrancesco | Jun 10, 2001 | 6 min read
Europeans have destroyed 4.5 million cows since 1996, the height of the epidemic in the United Kingdom, because they were believed to be at risk for mad cow disease (bovine spongiform encephalopathy, or BSE).1 Necropsies, however, showed that only a few hundred thousand of them actually were infected.2 Had a diagnostic test for mad cow disease existed when this epidemic erupted, these numbers might have been different. But no such test did exist. The only available assay was a bioassay in which
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Drug Makers on the Apoptotic Trail
Ted Agres | Jun 24, 2001 | 4 min read
Apoptosis, a key process in the development of embryonic tissue differentiation, later helps to regulate the normal cellular life cycle by destroying damaged cells. When something goes awry, too little apoptosis can make cancer cells resistant to chemotherapy and even death-defiant. At the other extreme, premature or excessive apoptosis has been linked to neurodegenerative diseases, such as Alzheimer's, and to nerve cell loss in strokes. Not surprisingly, many major pharmaceutical companies rec
The Proteasome: A Powerful Target for Manipulating Protein Levels
John Hines and Craig M. Crews | May 1, 2017 | 10+ min read
The proteasome’s ability to target and degrade specific proteins is proving useful to researchers studying protein function or developing treatments for diseases.
Illuminating Behaviors
Douglas Steinberg | Jun 1, 2003 | 6 min read
Courtesy of Genevieve Anderson If not for Nobel laureates Thomas Hunt Morgan, Eric R. Kandel, and Sydney Brenner, the notion of a general behavioral model might seem odd. Behaviors, after all, are determined by an animal's evolutionary history and ecological niche. They are often idiosyncratic, shared in detail only by closely related species. But, thanks to Morgan's research in the early 20th century, and Kandel's and Brenner's work over the past 35 years, the fly Drosophila melanogaster, t

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