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The Scientist

» drug discovery, microbiology and immunology

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image: FDA Reform to Boost US Economy?

FDA Reform to Boost US Economy?

By | March 5, 2013

Two experts propose replacing Phase 3 trials with smaller, faster alternatives and post-market surveillance to invigorate the pharmaceutical industry.

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image: Antibody-Dependent Enhanced (ADE) Immunity

Antibody-Dependent Enhanced (ADE) Immunity

By | March 2, 2013

The method to the dengue virus's maddening infectiousness.

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image: Antibiotic Bouncer

Antibiotic Bouncer

By | March 1, 2013

Contrary to previous assumptions that macrolide antibiotics completely block the exit tunnel of ribosomes, new evidence shows that some peptides are allowed to pass.

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image: Bacterial Buddies

Bacterial Buddies

By | March 1, 2013

A chance encounter with a crab apple tree leads to the discovery of a new bacterial species and clues to the evolution of insect endosymbionts.

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image: Blue Biotech

Blue Biotech

By | March 1, 2013

Systems biologist Lone Gram describes her approach to combing the oceans for novel compounds that may be useful in the fight against pathogens.

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image: Sea Change

Sea Change

By | March 1, 2013

A normally land-based microbiologist sets sail to find the building blocks of novel antibiotics in marine bacteria.

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image: Teenage Drug Hunter

Teenage Drug Hunter

By | March 1, 2013

An Oregon teenager spent a summer in a New York biochemistry lab helping to discover a novel molecule that could become the next commercial nonaddictive painkiller.

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image: Bedeviled by Dengue

Bedeviled by Dengue

By | March 1, 2013

The global spread of dengue virus has immunologists and public-health experts debating the best way to curb infection.

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image: Do Mice Make Bad Models?

Do Mice Make Bad Models?

By | February 11, 2013

A study suggests that some mouse models do not accurately mimic human molecular mechanisms of inflammatory response, but other mouse strains may fare better.

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image: Stem Cells: Safe Haven For TB

Stem Cells: Safe Haven For TB

By | February 5, 2013

Tuberculosis bacteria find shelter from drugs and the body’s defenses in bone marrow stem cells.

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