Two experts propose replacing Phase 3 trials with smaller, faster alternatives and post-market surveillance to invigorate the pharmaceutical industry.
Two experts propose replacing Phase 3 trials with smaller, faster alternatives and post-market surveillance to invigorate the pharmaceutical industry.
The method to the dengue virus's maddening infectiousness.
Contrary to previous assumptions that macrolide antibiotics completely block the exit tunnel of ribosomes, new evidence shows that some peptides are allowed to pass.
A chance encounter with a crab apple tree leads to the discovery of a new bacterial species and clues to the evolution of insect endosymbionts.
Systems biologist Lone Gram describes her approach to combing the oceans for novel compounds that may be useful in the fight against pathogens.
A normally land-based microbiologist sets sail to find the building blocks of novel antibiotics in marine bacteria.
An Oregon teenager spent a summer in a New York biochemistry lab helping to discover a novel molecule that could become the next commercial nonaddictive painkiller.
The global spread of dengue virus has immunologists and public-health experts debating the best way to curb infection.
A study suggests that some mouse models do not accurately mimic human molecular mechanisms of inflammatory response, but other mouse strains may fare better.
Tuberculosis bacteria find shelter from drugs and the body’s defenses in bone marrow stem cells.