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image: How Poison Frogs Avoid Poisoning Themselves

How Poison Frogs Avoid Poisoning Themselves

By | September 21, 2017

Amphibians resist their own chemical defenses with amino acid modifications in the sequence for a target receptor.

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image: CRISPR Used in Human Embryos to Probe Gene Function

CRISPR Used in Human Embryos to Probe Gene Function

By | September 20, 2017

OCT4 is necessary for blastocyst formation in the human embryo, researchers report.

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A study of a simple marine animal suggests that the common ancestor of cnidarians and bilaterians may have had three germ layers instead of two.

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image: How Immune Receptors Got into Mouse Noses

How Immune Receptors Got into Mouse Noses

By | September 1, 2017

A study traces proteins’ evolution from the immune to the olfactory system.

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image: Chemogenetics Doesn’t Work Like Many Thought

Chemogenetics Doesn’t Work Like Many Thought

By | August 4, 2017

A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.

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image: Endocannabinoids in the Groove

Endocannabinoids in the Groove

By | July 17, 2017

The system responsible for the buzz humans get from marijuana plays a passel of physiological roles outside the brain.

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The cell-surface receptor, SIRP-alpha, initiates the innate immune response in hosts.  

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Research shows that human immunity develops much earlier than previously thought, but functions differently in adults.

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The 19th century biologist’s drawings, tainted by scandal, helped bolster, then later dismiss, his biogenetic law.

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Time-lapse imaging shows the immune cells transferring chemical signals during pigment pattern formation in developing zebrafish.

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