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tag dna damage response culture

Broken DNA
DNA Damage Viewed with Unprecedented Clarity
Amanda Heidt | Aug 15, 2022 | 3 min read
A new tool called PRISM draws on virus-host interactions and a DNA repair pathway to help researchers visualize how cellular stress may contribute to neurodegenerative disease.
3D representation of a DNA helix and with a base offset from the main helix, illustrating the concept of base editing.
A CRISPR Alternative for Correcting Mutations That Sensitize Cells to DNA Damage
Deanna MacNeil, PhD | Oct 10, 2022 | 3 min read
Researchers turned to base editors to correct mutations causing the rare genetic disease Fanconi anemia without inducing double-strand DNA breaks.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Yeast Made to Harvest Light Hint at Evolution’s Past
Kamal Nahas, PhD | Feb 21, 2024 | 6 min read
Scientists transferred light-harvesting proteins into yeast for the first time, shining a light on the past lives of eukaryotic cells.
Does DNA Damage Cause Cancer?
Charles Q. Choi | Jun 1, 2007 | 4 min read
Back-to-back studies pose double-strand breaks as initiating tumorigenesis.
Damage Control
Bob Grant | Mar 1, 2009 | 4 min read
Researchers unlock a treasure trove of information about how cells sense and respond to DNA damage.
An automated sampler that is collecting a sample from a sewer line.
Tracking Community Health Through Wastewater Surveillance
Charlene Lancaster, PhD | Feb 1, 2024 | 8 min read
By monitoring disease biomarkers within wastewater, researchers gain insight into disease prevalence within communities.
Dealing with damage
Jonathan Weitzman(jonathanweitzman@hotmail.com) | Jun 23, 2002 | 1 min read
Genes induced by DNA-damaging agents appear not to be those required for survival.
small, circular bones individually labeled and packaged in plastic bags
2,000-Year-Old Salmon DNA Reveals Secret to Sustainable Fisheries
Dan Robitzski | Nov 29, 2021 | 5 min read
Genomic analysis of ancient chum salmon bones and cultural knowledge from the Tsleil-Waututh Nation suggest that people in the Pacific Northwest managed fisheries for thousands of years by harvesting males and releasing females.

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