Subscribe
Menu
Login
Login
Subscribe
News & Opinion
Publications
AN INTERACTIVE EXPERIENCE
Current Issue
March 2024
View This Issue
Archives
Features
Quarterly Magazine
Current Issue
Spring 2024
View This Issue
Archives
Features
Categories
Biochemistry
Cancer
Cell Biology
Community
Drug Development
Environment
Evolution
Genetics
Immunology
Microbiology
Neuroscience
Physiology
Public Health
Zoology
TS University
Scientific Services
Brush Up Summaries
Technique Talks
Journal Club
TS SciComm
Multimedia
Crossword Puzzles
eBooks
Infographics
Podcasts
Research Products Blog
Research Articles
Science Snapshot
Slideshows
Videos
Words for Nerds
Webinars
ADVERTISEMENT
404
Not Found
Is this what you were looking for?
tag double strand breaks culture disease medicine
A CRISPR Alternative for Correcting Mutations That Sensitize Cells to DNA Damage
Deanna MacNeil, PhD
| Oct 10, 2022
| 3 min read
Researchers turned to base editors to correct mutations causing the rare genetic disease Fanconi anemia without inducing double-strand DNA breaks.
DNA breakage surprisingly rare
Andrea Gawrylewski
| May 28, 2007
| 3 min read
Double-strand breaks during replication occur much less frequently than previously thought
Stem Cell Editing Repairs Severe Immunodeficiency
Kamal Nahas, PhD
| Mar 20, 2024
| 5 min read
Scientists hoping to treat immunodeficiencies using gene therapy have found a way to edit stem cells in mice without disrupting gene regulation.
DNA Damage Linked to Brain Overgrowth in Autism
Abby Olena, PhD
| Feb 5, 2020
| 4 min read
Cell lines from individuals with macrocephalic autism spectrum disorder have an increased number of double-strand breaks in the DNA of long neural genes.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Turning on the Bat Signal
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Optimizing Gene Editing with PARP1 CRISPR Plasmids
The Scientist
and Santa Cruz Biotechnology, Inc.
| Jan 24, 2024
| 3 min read
CRISPR plasmids provide a robust solution for streamlining human cell transfection workflows.
All Roads Lead to Genome Editing
Danielle Gerhard, PhD
| Feb 9, 2024
| 6 min read
Shondra Pruett-Miller has taken many paths in her career with her love of genome editing always as a guiding light.
The Future of Gene Therapy for a Rare Pediatric Autoimmune Disease
Niki Spahich, PhD
| Jul 10, 2023
| 3 min read
By editing a mutated immune regulatory gene in patient cells, Rosa Bacchetta brings hope to those suffering from IPEX syndrome.
Skin Bacteria May Trigger Lupus: Mouse Study
Natalia Mesa, PhD
| Oct 28, 2022
| 3 min read
Staphylococcus aureus
appears to be the culprit.
Run a Search
ADVERTISEMENT