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tag computational biology evolution cell molecular biology

Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Infusion of Artificial Intelligence in Biology
Meenakshi Prabhune, PhD | Feb 23, 2024 | 10 min read
With deep learning methods revolutionizing life sciences, researchers bet on de novo proteins and cell mapping models to deliver customized precision medicines.
Molecular Biology
The Scientist Staff | Aug 22, 1993 | 2 min read
M. Leid, P. Kastner, R. Lyons, et al., "Purification, cloning and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently," Cell, 68:377-95, 1992. Mark Leid (Oregon State University, Corvallis): "The diverse effects of retinoic acid (RA) on development, cellular growth and differentiation, and homeostasis are mediated by two families of RA receptors that arose independently during evolution and belong to the steroid/thyroid hormone super
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Molecular Biology
The Scientist Staff | Mar 1, 1992 | 2 min read
D.W. Nebert, D.R. Nelson, M.J. Coon, R.W. Estabrook, et al., "The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature," DNA and Cell Biology, 10:1-14, 1991. Daniel W. Nebert (University of Cincinnati Medical Center): "This review is the third in a series of comprehensive, up- to-date compilations of data about members of the large cytochrome P450 gene superfamily. It serves to organize a large--and growing--body of sequencing and mapping data on 154 P450 genes
MOLECULAR BIOLOGY
Paris | Jul 19, 1992 | 1 min read
Michel Philippe (Universite de Rennes, Rennes Cédex, France): "In yeast, two critical points of the cell cycle (Start and G1/S) are regulated by the same protein. This protein, called p34cdc2, is coded by the genes cdc2 in Schizzosaccharomyces pombe and CDC28 in Saccharomyces cerevisiae. By complementation of yeast mutants, proteins from higher eucaryotes homologous to cdc2 have been cloned. Moreover, p34cdc2 has been shown to be one of the main components of the well-known M-phase promotin
The image shows six different panels containing cells. On each panel, the cells are labelled using a different fluorescent dye that highlights features of a specific organelle within the cells.
Cell Painting: Exploring the Richness of Biological Images
Mariella Bodemeier Loayza Careaga, PhD | Sep 8, 2023 | 4 min read
By coloring different organelles simultaneously, cell painting allows scientists to pick up subtle changes in cell function in response to drugs and other perturbations.
Molecular Biology
The Scientist Staff | Nov 11, 1990 | 2 min read
(The Scientist, Vol:4, #22, pg. 20, November 12, 1990) (Copyright, The Scientist, Inc.) -------- M.P. Scott, J.W. Tamkun, G.W. Hartzell III, "The structure and function of the homeodomain," Biochimica et Biophysica Acta, 989, 25-48, 28 July 1989. Matthew P. Scott (Stanford University School of Medicine, Calif.): "The review is really a celebration of an exciting time in the study of the DNA-binding protein fragment called a homeodomain. People in dozens of labs are contributing to the fun, fin
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.

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