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tag bugs culture genetics genomics microbiology

Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Fish in a big blue aquarium
Microbes Responsible for Stealing Aquarium Medicine
Amanda Heidt | Feb 1, 2022 | 6 min read
Researchers discover that bacteria break down medicinal compounds for their nitrogen, solving a mystery that has vexed aquatic veterinarians for years.
an illustration of bacteria
Genome Data Enable Capture of Elusive Microbes
Ruth Williams | Jan 13, 2020 | 3 min read
Using reverse genetics, researchers create antibodies to reel in previously uncultured bacteria.
a photo of ampules stored in wire racks
Scripps Acquires Pfizer’s Massive Microbial Library
Jef Akst | Jan 9, 2020 | 5 min read
The East Coast campus of the research institute received shipments of freeze-dried or frozen samples of more than 210,000 microbial strains, which scientists plan to mine for potentially useful natural products.
Cross section of an organic cell with intracellular organelles
How Intracellular Bacteria Hijack Your Cells
Catherine Offord | Dec 1, 2022 | 10+ min read
Scientists studying pathogens such as Chlamydia, Legionella, and Listeria get a master class in how to control the internal workings of mammalian cells.
Bug-Busting Grows Sophisticated
Douglas Steinberg | Dec 10, 2000 | 8 min read
Credit: William Jacobs, Albert Einstein College of MedicineTuberculosis bacterium The battles that scientists wage against bacteria and viruses resemble chess matches between grandmasters and supercomputers. Highly intelligent people are pitted against entities that aren't conscious but that nevertheless hold two big advantages. Populated by hosts of individually sensitive microchips or microorganisms, these entities can react with lightning speed. And tutored intensively by computer programmers
black-and-white image of an open mouth
The Common Mouth Microbe That Keeps Popping Up in Tumors
David Adam | Dec 15, 2021 | 6 min read
Lab studies link the oral bacteria Fusobacterium nucleatum to cancers from the gut to the head and neck. Could targeting the microbe tackle tumors?
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Gene Exchange Among Gut Bacteria Is Linked to Industrialization
Catherine Offord | Mar 31, 2021 | 5 min read
A study of human populations around the world detects differing rates of horizontal gene transfer in the microbiome depending on what kind of society those people live in.

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