Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 

Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.

The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.

A new platform for screening astrocyte reactivity helps researchers uncover potential therapeutic interventions to treat neurodegenerative conditions.

With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.

A.D. Friedman, W.H. Landschulz, S.L. McKnight, "CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells," Genes & Development, 3: 1314-22, 1989. Alan D. Friedman (Johns Hopkins Oncology Center, Baltimore): "CCAAT/enhancer binding protein (C/EBP) is perhaps best known as the prototypical basic region-leucine zipper DNA-binding protein (Science, 243:1681-88, 1989). This paper, however, represents part of the earliest efforts of the McKnight labo

A 3D variation of pooled CRISPR screens could connect the dots between autism spectrum disorder genetics and cell fate pathways in the developing brain.

S. Akira, T. Hirano, T. Taga, T. Kishimoto, "Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF)," FASEB Journal, 4:2860-67, 1990. Shizuo Akira (Institute for Molecular and Cellular Biology, Osaka University, Japan): "Interleukin-6 (IL-6) is a pleiotropic cytokine that plays a central role in defense mechanisms, including the immune response, acute phase reaction, and hematopoiesis. Since our success in the cloning of the IL-6 cDNA in 1985, our group has been study