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tag dna immunology cell molecular biology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
Image showing monoclonal antibody treatment
The Resilience of Monoclonal Antibodies and their Makers
Laura Tran, PhD | Mar 15, 2024 | 10+ min read
The road to developing monoclonal antibodies for effectively targeting cancer was paved with tenacity, passion, and strokes of luck.
Artist’s rendition of red SARS-CoV-2 coronaviruses floating near blue strands of DNA.
COVID-19 Infections May Reshape Genetic Landscape
Holly Barker, PhD | Mar 30, 2023 | 3 min read
SARS-CoV-2 infection triggers structural changes in the host cell’s DNA, which provide a molecular explanation for long COVID, a new study suggests. 
Molecular Biology
The Scientist Staff | Sep 1, 1991 | 1 min read
S. Ghosh, D. Baltimore, "Activation in vitro of NF-kB by phosphorylation of its inhibitor IkB," Nature, 344:678-82, 1990. Sankar Ghosh (Whitehead Institute for Biomedical Research, Cambridge, Mass.): "This paper brings together two areas of rapidly moving research: the role of protein phosphorylation and control of transcriptional regulation. The inhibitor IkB not only keeps the transcription factor NF-kB in the cytoplasm--away from DNA--but also directly prevents it from binding to DNA. By sh
A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | Feb 13, 2024 | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.

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