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tag vertebrates cell molecular biology culture

Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
Molecular Biology
The Scientist Staff | Feb 20, 1994 | 2 min read
S. Matsuda, H. Kosako, K. Takenaka, K. Moriyama, H. Sakai, T. Akiyama, Y. Gotoh, E. Nishida, "Xenopus MAP kinase activator: identification and function as a key intermediate in the phosphorylation cascade," The EMBO Journal, 11:973-82, 1992. Eisuke Nishida (Department of Genetics and Molecular Biology, Institute for Virus Research, Kyoto University, Japan): "MAP kinases have been described as serine/threonine kinases that are acti
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Top 7 in molecular biology
Megan Scudellari | Jun 14, 2011 | 3 min read
A snapshot of the most highly ranked articles in molecular biology, from Faculty of 1000.
Image of pancreatic organoids under a microscope with immunofluorescent staining
Pancreatic Organoids Take the Stage
Laura Tran, PhD | Dec 1, 2023 | 2 min read
Meritxell Huch tackled her pipedream of growing three-dimensional pancreatic tissue in a dish.
Molecular Demolition
Gregory Smutzer | Feb 17, 2002 | 9 min read
The ability of cells to degrade and rearrange extracellular matrix proteins is crucial for an organism's growth and development. Nearly 40 years ago, Jerome Gross and Charles Lapiere discovered that when tadpole tail fins resorb, their skin releases an enzyme that degrades native collagen triple helixes in the underlying support matrix.1 This enzyme, called collagenase, is present in a wide variety of vertebrates, invertebrates, and plants. Critical as it is, collagenase is just one member of a

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