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tag australia developmental biology

An illustration of flowers in the shape of the female reproductive tract
Uterus Transplants Hit the Clinic
Jef Akst | Aug 1, 2021 | 10+ min read
With human research trials resulting in dozens of successful deliveries in the US and abroad, doctors move toward offering the surgery clinically, while working to learn all they can about uterine and transplant biology from the still-rare procedure.
New Technologies Shed Light on Caveolae
Ben Nichols | Jun 1, 2018 | 10+ min read
The functions of the cellular invaginations identified more than half a century ago are now beginning to be understood in detail.
STAP Drama Continues
Jef Akst | Mar 24, 2014 | 1 min read
Nearly two months after researchers published papers showing that they could induce pluripotency with an external stressor, the work’s validity is still being challenged.
Notable
Jeffrey Perkel | Jan 6, 2002 | 4 min read
J.A. Camarero et al., "Peptide chemical ligation inside living cells: In vivo generation of a circular protein domain," Bioorganic and Medicinal Chemistry, 9[9]:2479-84, September 2001. F1000 Rating: Recommended "To investigate whether chemo-selective peptide ligations work in vivo, the authors demonstrate the in vivo head-to-tail cyclization of a bioactive SH3 domain using native chemical ligation. The protein precursor was constructed using a clever combination of an intein-fusion protein an
NAS Honors Sagan And 14 Other Science Achievers
Neeraja Sankaran | Apr 17, 1994 | 8 min read
Three of the 13 awards this year are going to astronomers, including the academy's highest honor--the Public Welfare Medal--which is being given to Carl E. Sagan, 59, David Duncan Professor of Astronomy and Space Sciences at Cornell University, Ithaca, N.Y. Every year, NAS presents this medal (the only award without an accompanying cash prize) to an individual who has made extraordinary use of science for the public good. Perhaps
NAS Honors Sagan And 14 Other Science Achievers
Neeraja Sankaran | Apr 17, 1994 | 8 min read
Three of the 13 awards this year are going to astronomers, including the academy's highest honor--the Public Welfare Medal--which is being given to Carl E. Sagan, 59, David Duncan Professor of Astronomy and Space Sciences at Cornell University, Ithaca, N.Y. Every year, NAS presents this medal (the only award without an accompanying cash prize) to an individual who has made extraordinary use of science for the public good. Perhaps
Ribozymes: Hearkening Back to an RNA World
Jeffrey Perkel | Sep 15, 2002 | 9 min read
Illustration: Ned Shaw LIKE MOLECULAR TOY-MAKERS, ribozyme researchers create tools with evolutionary, diagnostic, and therapeutic applications. Nearly 20 years ago, Tom Cech and Sidney Altman discovered that some naturally occurring RNAs could perform enzymatic reactions, earning these researchers the 1989 Nobel Prize in chemistry. Scientists have now identified several examples of RNA enzymes, or ribozymes. Most make or break the phosphodiester bonds in nucleic acid backbones, but some
Alternative Splicing Goes Mainstream
Sam Jaffe | Dec 14, 2003 | 10 min read
In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative splicing, which may allow a lowly 30,000-gene genome to produce the dizzying variety of proteins that some believe is necessary to produce beings as complex as humans. Alternative splicing--the post-transcriptional editing process that can result in various mRNAs--was previously seen as an interesting but relatively uncommon sidesh
Preimplantation Genetic Diagnosis: The Next Big Thing?
Ricki Lewis | Nov 12, 2000 | 9 min read
Courtesy of David Hill, ART Reproductive Center Inc.Two separated blastomeres subjected to FISH analysis to check the chromosomes. In early October, preimplantation genetic diagnosis (PGD) made headlines when a Colorado couple used assisted reproductive technology (ART) to have a baby named Adam, whose umbilical cord stem cells could cure his six-year-old sister Molly's Fanconi anemia.1 When Adam Nash was a ball of blastomere cells, researchers at the Reproductive Genetics Institute at Illinois
One Step Beyond: Going Beyond Genomics With Proteomics And Two-Dimensional Gel Technology
Laura Defrancesco | Jan 3, 1999 | 10+ min read
Proteomes and 2D Gel Apparatus Providers Big science has moved on to proteins. With the new brand of science termed proteomics--named by the Australians Marc Wilkins and Keith Williams to mean the "set of PROTEins encoded by the genOME"--the push is on around the globe to produce a complete description of a cell/tissue/organism in terms of the proteins produced. The challenge is all the greater because the expressed protein pattern changes with time and environment--responding to developmenta

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