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image: Tracing Zika’s Spread Through Genetics

Tracing Zika’s Spread Through Genetics

By | May 25, 2017

DNA sequencing reveals that the virus responsible for the recent outbreak in the Americas originated in Brazil in 2014 and circulated undetected for months before the first cases were reported.

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image: Quick and Cheap Zika Detection

Quick and Cheap Zika Detection

By | May 3, 2017

A heat block, a truck battery, and a novel RNA amplification assay make for in-the-field surveillance of the virus.

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Studies of infected rhesus monkeys reveal the virus’s long-term hiding places in the body.

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image: Mutations Linked to Secondary Cancers

Mutations Linked to Secondary Cancers

By | April 4, 2017

Childhood cancer survivors with mutations in certain cancer-risk genes have a higher risk of developing additional neoplasms later in life, according to research presented at the American Association for Cancer Research annual meeting.

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image: Contributors

Contributors

By | April 1, 2017

Meet some of the people featured in the April 2017 issue of The Scientist.

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image: Hitting It Out of the Park

Hitting It Out of the Park

By | April 1, 2017

Cancer can be as evasive and slippery as a spitball, but new immunotherapies are starting to connect.

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image: Location, Location, Location

Location, Location, Location

By | April 1, 2017

Since first proposing that a cell’s function and biology depend on its surroundings, Mina Bissell continues to probe the role of the extracellular matrix.

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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image: Circadian Rhythms Influence Treatment Effects

Circadian Rhythms Influence Treatment Effects

By | April 1, 2017

Across many diseases, taking medication at specific times of day may make the therapy more effective.

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