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tag nerve growth factor beta disease medicine evolution

Pursuing Growth Factors For Speedier Wound Healing
Thomas Mustoe | Nov 27, 1988 | 4 min read
The fundamental role of polypeptide growth factors in stimulating the proliferation of cells and in regulating cell growth (both positively and negatively) has been increasingly appreciated in the last several years (see The Scientist, October 31, page 13). The first growth factor to be discovered—nerve growth factor, in 1951—was initially thought to be an isolated phenomenon. But over the last decade, several other growth factors have been characterized. The study of growth factors
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Amyloid plaques on axons of neurons
The Misunderstood Proteins of Neurodegeneration
Catherine Offord | Aug 1, 2022 | 10+ min read
The normal functions of peptides that aggregate in Alzheimer’s, Parkinson’s, and Huntington’s have been largely overlooked by scientists, but some argue that they are critical for understanding the development of disease.
Do Microbes Trigger Alzheimer’s Disease?
Jill U. Adams | Sep 1, 2017 | 10 min read
The once fringe idea is gaining traction among the scientific community.
Can Destroying Senescent Cells Treat Age-Related Disease?
Katarina Zimmer | Mar 1, 2020 | 10+ min read
A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.
Movement Disorders: Less of a Black Box
Jean Mccann | Sep 17, 2000 | 7 min read
Shake the family tree of a patient with a movement disorder, and more and more genes are apt to tumble out. Parkinson's disease and many less well-known movement disorders are now considered to be more familial than scientists had previously thought. "When it comes to Parkinson's disease, the important role of genetics as a decisive factor in the appearance and evolution of the disease is gaining more and more ground," says Eduard Tolosa, chairman of the department of neurology at the University
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
Bite makes way for brain
Brendan Maher(bmaher@the-scientist.com) | Mar 23, 2004 | 4 min read
A single mutation may have caused gross anatomical changes that spurred human evolution
The Proteasome: A Powerful Target for Manipulating Protein Levels
John Hines and Craig M. Crews | May 1, 2017 | 10+ min read
The proteasome’s ability to target and degrade specific proteins is proving useful to researchers studying protein function or developing treatments for diseases.

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