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tag blood spot cards genetics genomics

Blood Spots Are Epigenetic Time Capsules
Sabrina Richards | Aug 22, 2012 | 3 min read
Researchers show that blood spotted onto Guthrie cards, usually at birth, can be a high quality source of methylated DNA for long-term epigenetic studies.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Genome Economy
Ricki Lewis | Jun 10, 2001 | 10 min read
The Human Genome Project's discovery1 that the human body runs on an instruction manual of a mere 35,000 or so genes--compared to the worm's 19,000, the fruit fly's 13,000, and the tiny mustard relative Arabidopsis thaliana's 25,000--placed humanity on an even playing field with these other, supposedly simpler, organisms. It was a humbling experience, but humility quickly gave way to awe with the realization that the human genome might encode 100,000 to 200,000 proteins. Scientists base this num
Reductio Ad Amino Acid
Bob Sinclair | Feb 1, 1999 | 10+ min read
Date: February 1, 1999Fusion/Tag Proteases TableProteolytic Enzymes TableTable 3Table 4 A proteome analysis aims to characterize all proteins expressed by an organism or tissue. The next step will be to correlate a protein profile with the appropriate genome, and beyond that researchers will want to understand the correlations between levels of proteins, co- and post-translational modifications, and cell or tissue activity. Many of the technologies that are necessary to realize this goal are de
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Identifying Those Remembered
Kelli Miller | Jun 9, 2002 | 8 min read
Last year, two Denver scientists theorized that a clinical instrument used to spot cancer mutations could speed up the normally tedious DNA identification process. Then the attacks of Sept. 11 occurred, and their work suddenly took on a sense of urgency. When the National Institute of Justice (NIJ) sent out a countrywide plea for information on new technologies that could assist in the investigation at Ground Zero, Phil Danielson, assistant professor of molecular biology at the University of Den
2019 Top 10 Innovations
The Scientist | Dec 1, 2019 | 10+ min read
From a mass photometer to improved breath biopsy probes, these new products are poised for scientific success.
DNA Chips Enlist in War on Cancer
Douglas Steinberg | Feb 20, 2000 | 10+ min read
Graphic: Cathleen Heard The boy had the classic symptoms of acute leukemia--low blood counts and tumor cells circulating in his bloodstream. But the diagnosis was tentative because the tumor cells looked atypical for leukemia. So doctors extracted RNA from the cells, made cDNAs from the RNA, and incubated the cDNAs with a chip bearing thousands of single-stranded gene fragments on its glass surface. The hybridization pattern suggested, surprisingly, that the boy had a muscle tumor. After confirm

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