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image: Oligonucleotide Therapeutics Near Approval

Oligonucleotide Therapeutics Near Approval

By | December 1, 2016

Successful late-stage clinical trials could mark the maturation of a new drug development platform, but the path to commercialization is not without hurdles.

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Lawyers for PubPeer have obtained and posted the full investigation report from Wayne State University, which lists more than 140 misconduct allegations against pathologist Fazlul Sarkar.

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image: More Success Fixing Sickle Cell Gene with CRISPR

More Success Fixing Sickle Cell Gene with CRISPR

By | November 9, 2016

Researchers say they have sufficient in vitro and animal data to apply for human testing.

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Family members with a certain gene variant had unnecessary interventions, highlighting the potential hazards of precision medicine.

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image: Zika Update

Zika Update

By | October 24, 2016

Virus’s effect on RNA methylation; identifying brain cells targeted by Zika; virus found in vaginal secretions for two weeks after infection; updated CDC recommendations for Miami

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image: Week in Review: October 17–21

Week in Review: October 17–21

By | October 21, 2016

Report finds that pathologist involved in anonymous defamation case committed multiple acts of misconduct; growing eggs from stem cells; neutrophils’ role in metastasis; convergent evolution in birds

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image: Misconduct Finding Could Impact PubPeer Litigation

Misconduct Finding Could Impact PubPeer Litigation

By | October 19, 2016

Wayne State University’s conclusion that pathologist Fazlul Sarkar committed research misconduct could affect the ongoing legal proceedings related to anonymous critics of his work.

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image: Nixing NETs to Prevent Metastasis

Nixing NETs to Prevent Metastasis

By | October 19, 2016

Researchers discover that neutrophil extracellular traps help cancers spread, and design enzyme-loaded nanoparticles to destroy them.

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Once implanted in mice, the edited stem cells produced normal hemoglobin.

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image: Deep-Sea Viruses Destroy Archaea

Deep-Sea Viruses Destroy Archaea

By | October 12, 2016

Viruses are responsible for the majority of archaea deaths on the deep ocean floors, scientists show.

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