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tag encode culture disease medicine genetics genomics
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
Identical Twins Carry Distinctive Epigenetic Marks: Study
Chloe Tenn
| Sep 30, 2021
| 2 min read
Researchers found more than 800 sites in the genome where the twins bore the same chemical tags.
Humans Rely on Gut Bacteria for an Enzyme that Prevents Jaundice
Kamal Nahas, PhD
| Feb 16, 2024
| 5 min read
An absence of bilirubin-producing gut microbes may predispose individuals to some diseases, including inflammatory bowel disease.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Redesigning Medicine Using Synthetic Biology
Alison Halliday, PhD,
Technology Networks
| Jun 21, 2023
| 5 min read
Drawing inspiration from nature, synthetic biology offers exciting opportunities to transform the future of medicine.
Delivering Prime Editors With Virus-like Particles
Deanna MacNeil, PhD
| Mar 11, 2024
| 3 min read
An iterative engineering approach to improve prime editor delivery helped scientists correct genetic vision defects in mice.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD
| Mar 12, 2024
| 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
Turning on the Bat Signal
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD
| Mar 15, 2024
| 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
Genetic Variant Discovered in Amish Protects from Heart Disease
Abby Olena, PhD
| Dec 2, 2021
| 3 min read
Researchers link a missense mutation in the
B4GALT1
gene to lower levels of LDL cholesterol and the blood clotting factor fibrinogen.
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