Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.

Researchers developed a “test tube” so tiny that it can hold a single cell. These vials enabled them to connect protein secretion levels with surface markers and transcriptome data from the same cell. 

Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.

With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.

Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.

Beyond The Scientist’s coverage of COVID-19’s molecular underpinnings were many other stories highlighting the advances made in scientists’ understanding of the biology of cells.

A guide to DNA-encoded libraries for drug discovery

Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.

K.C. Garcia, M. Degano, R.L. Stanfield, A. Brunmark, M.R. Jackson, P.A. Peterson, L. Teyton, I.A. Wilson, "An alpha-ß T cell receptor structure at 2.5Å and its orientation in the TCR-MHC complex," Science, 274:209-19, 1996. (Cited in more than 240 papers since publication) Comments by Ian A. Wilson, professor of molecular biology at The Scripps Research Institute in La Jolla, Calif. D.N. Garboczi, P. Ghosh, U. Utz, Q.R. Fan, W.E. Biddison, D.C. Wiley, "Structure of the complex bet