With deep learning methods revolutionizing life sciences, researchers bet on de novo proteins and cell mapping models to deliver customized precision medicines.

Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 

Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.

Drawing inspiration from nature, synthetic biology offers exciting opportunities to transform the future of medicine.

Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 

A new platform for screening astrocyte reactivity helps researchers uncover potential therapeutic interventions to treat neurodegenerative conditions.

C.V. Gunther, J.A. Nye, R.S. Bryner, B.J. Graves, "Sequence-specific DNA binding of the proto-oncoprotein ets-1 defines a transcriptional activator sequence within the long terminal repeat of the Moloney murine sarcoma virus," Genes & Development, 4:667-79, 1990. Barbara J. Graves (University of Utah School of Medicine, Salt Lake City): "This paper reported our laboratory's serendipitous discovery that ets-1 encodes a sequence-specific DNA-binding protein. Our results implicated this proto-onc

A new study confirms reports of membrane-bound RNA molecules and points to their role in neutrophil migration.

Through immunofluorescence microscopy, a rainbow of stains shows Amy Engevik where proteins go in health and disease states.

Beyond The Scientist’s coverage of COVID-19’s molecular underpinnings were many other stories highlighting the advances made in scientists’ understanding of the biology of cells.