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The Scientist

» melanoma and developmental biology

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image: Viral Immunotherapy for Melanoma

Viral Immunotherapy for Melanoma

By | May 28, 2015

Phase 3 data from a clinical trial show a positive response to a melanoma treatment based on a modified herpesvirus.

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image: Dino Snouts from Chicken Beaks

Dino Snouts from Chicken Beaks

By | May 13, 2015

Researchers tweak gene expression in chicken embryos that may have been crucial to the evolutionary transition from dinosaur noses to bird bills.

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T-cell receptor repertoires could help researchers determine whether a certain treatment will work for a given cancer patient. 

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Viral Protector

By | April 21, 2015

A retrovirus embedded in the human genome may help protect embryos from other viruses, and influence fetal development.

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image: Personalized Cancer Vaccines

Personalized Cancer Vaccines

By | April 2, 2015

A dendritic cell vaccine targeting melanoma patients’ tumor-specific mutations can activate a broad range of cancer-fighting T cells. 

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Contributors

By | April 1, 2015

Meet some of the people featured in the April 2015 issue of The Scientist.

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From Many, One

By | April 1, 2015

Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?

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Short, Strong Signals

By | March 25, 2015

Methylation increases both the activity and instability of the signaling protein Notch.

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The Dark Side of Melanin

By | February 19, 2015

Researchers uncover a previously unknown way UV light can act on melanin, spurring cancer-causing mutations hours after sun exposure.

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Fertility Treatment Fallout

By | January 1, 2015

Mouse offspring conceived by in vitro fertilization are metabolically different from naturally conceived mice.

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