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tag light sheet microscopy culture microbiology developmental biology

Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
Microscopy image of a cricket embryo, illuminated in green, pinched near one end, with one side full of bright green dots representing cell nuclei
How Wandering Nuclei Shape Developing Embryos
Viviane Callier | Jul 29, 2022 | 3 min read
As cricket blastoderms form, cell nuclei are pulled into an egg’s remaining empty space to form the new cell layers that will shape the developing animal.
A scanning electron micrograph of a coculture of E. coli and Acinetobacter baylyi. Nanotubes can be seen extending from the E. coli.
What’s the Deal with Bacterial Nanotubes?
Sruthi S. Balakrishnan | Jun 1, 2021 | 10+ min read
Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?
New Technologies Shed Light on Caveolae
Ben Nichols | Jun 1, 2018 | 10+ min read
The functions of the cellular invaginations identified more than half a century ago are now beginning to be understood in detail.
Top Ten Innovations 2011
The Scientist | Jan 1, 2012 | 10+ min read
Our list of the best and brightest products that 2011 had to offer the life scientist
The Scientist Staff | Mar 28, 2024
Beyond Film: Laboratory Imagers
Jorge Cortese | Apr 1, 2002 | 9 min read
Years ago, researchers had only one data-imaging option: autoradiography. These scientists tagged samples—whether nucleic acid, protein, cell, or tissue—with radioactive labels, and captured images on film. Safety concerns, convenience, and sensitivity, spurred the development of alternative techniques, and today, researchers can choose from a range of options, including fluorescence, chemifluorescence, and chemiluminescence, in addition to autoradiography. Fluorescence occurs when
Advances in the functional characterization of newly discovered microproteins hint at their diverse roles  in health and disease
The Dark Matter of the Human Proteome
Annie Rathore | Apr 1, 2019 | 10 min read
Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.
Updated July 9
Track COVID-19 Vaccines Advancing Through Clinical Trials
The Scientist | Apr 7, 2020 | 10+ min read
Find the latest updates in this one-stop resource, including efficacy data and side effects of approved shots, as well as progress on new candidates entering human studies.
Special Report: Cell Biologists Combine Old And New Tools
Ricki Lewis | Dec 9, 1990 | 10 min read
In 1663, English physicist Robert Hooke viewed cork under a microscope and observed that "these pores, or cells, were not very deep, but consisted of a great many little boxes." Although Hooke's discovery, which involved only the outer boundaries of cells, is considered the beginning of cell biology, it was nearly 200 years before two Germans, botanist Matthias Jakob Schleiden and physiologist Theodor Schwann, focused attention on the microcosm of life in the cell. Hooke, Schleiden, Schwann, a

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