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tag light sheet microscopy cell molecular biology immunology

Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
Live Imaging Using Light-Sheet Microscopy
Kelly Rae Chi | Nov 1, 2016 | 8 min read
How to make the most of this rapidly developing technique and a look at what's on the horizon
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
Planar imaging
Josh P. Roberts | Jun 1, 2008 | 2 min read
3D cultures of pancreatic tumor cells are embedded in agarose for imaging with light sheet-based fluorescence microscopy. Credit: Francesco Pampaloni / EMBL" />3D cultures of pancreatic tumor cells are embedded in agarose for imaging with light sheet-based fluorescence microscopy. Credit: Francesco Pampaloni / EMBL User: Ernst Stelzer, European Molecular Biology Laboratory, Heid
<em >Immunohistochemistry: Origins, Tips, and a Look to the Future</em>
Immunohistochemistry: Origins, Tips, and a Look to the Future
Steven Hrycaj, PhD | Oct 17, 2023 | 7 min read
An essential staining technique with a long history, immunohistochemistry (IHC) is being upgraded for modern research and clinical applications.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Improvements In Light Microscopy Lead To New Applications
Holly Ahern | Nov 24, 1991 | 6 min read
Hosts of new applications have turned the light microscope into an exquisitely sensitive measuring device that can be used to image dynamic cellular events right down to the molecular level. Indeed, dramatic improvements in optical microscopy have brought about a renaissance in the use of light microscopes in biology and medicine. And within the last few years, the combination of novel optical systems with video and digital image processing capabilities have opened up whole new fields of resear
The mouse peripheral nervous system with nerve cells farther away from the camera represented in yellow and pink, while nerves closer to the camera are shown in blue tones.
A Glowing Mouse Map
Mariella Bodemeier Loayza Careaga, PhD | Feb 1, 2024 | 2 min read
A whole-body immunostaining method allowed researchers to achieve cellular resolution at the whole-organism level.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Top 7 in Molecular Biology
Cristina Luiggi | Aug 16, 2011 | 3 min read
A snapshot of the most highly ranked articles in molecular biology, from Faculty of 1000

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