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tag heart attack disease medicine evolution

PCSK9 Drug Reduces Heart Disease Risk
Diana Kwon | Mar 21, 2017 | 2 min read
A cholesterol-lowering drug significantly cut the risk of heart attack and stroke in a recent study. But is it worth the steep cost?
Notebook
The Scientist Staff | Feb 14, 1999 | 5 min read
Editor's Note: The news items on this page all originated from the American Association for the Advancement of Science annual meeting in Anaheim, Calif., Jan. 21-26. PLAQUE ATTACK A host of studies have bitten off the task of linking periodontitis with coronary heart disease. But without more evidence, scientists may find any cause-and-effect relationship between tooth disease and heart attacks hard to swallow, admitted James D. Beck, professor of dental ecology, at the University of North Caro
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
microbiome
Do Commensal Microbes Stoke the Fire of Autoimmunity?
Amanda B. Keener | Jun 1, 2019 | 10+ min read
Molecules produced by resident bacteria and their hosts may signal immune cells to attack the body’s own tissues.
Novartis’s $9.7 Billion Purchase Includes Novel PCSK9 Inhibitor
Emily Makowski | Nov 25, 2019 | 2 min read
The pharmaceutical firm is buying The Medicines Company, which recently devoted its efforts into developing the cholesterol-lowering medication.
Histology of mouse lungs using purple and green staining on a white background. Left: a healthy lung. Right: a fibrotic lung.<br><br>
Immunotherapy Treats Fibrosis in Mice
Alejandra Manjarrez, PhD | Sep 15, 2022 | 4 min read
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
New MRIs on the Horizon
A. J. S. Rayl | Mar 19, 2000 | 7 min read
Courtesy of National Heart, Lung, and Blood InstituteMRI scans of the heart: upper left, torso with heart; upper right, cross section at aortic valve; lower left, lateral view of heart, pulmonic valve, and descending aorta; lower right, four-chamber view In the not too distant future, emergency rooms may well take on the aura of Star Trek's hospital bay. New, state-of-the-art magnetic resonance imaging (MRI) machines offer fast, efficient, and highly detailed data, allowing physicians to make im
Who Sleeps?
The Scientist and Jerome Siegel | Mar 1, 2016 | 10+ min read
Once believed to be unique to birds and mammals, sleep is found across the metazoan kingdom. Some animals, it seems, can’t live without it, though no one knows exactly why.
The Proteasome: A Powerful Target for Manipulating Protein Levels
John Hines and Craig M. Crews | May 1, 2017 | 10+ min read
The proteasome’s ability to target and degrade specific proteins is proving useful to researchers studying protein function or developing treatments for diseases.

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