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Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Molecular Multitasking
Carina Storrs | Aug 1, 2013 | 6 min read
Commercial kits use fluorescent beads to probe dozens of cytokines in one reaction.
Week in Review: February 23–27
Tracy Vence | Feb 27, 2015 | 3 min read
Stem cells in culture; engineered cancer biomarkers; small molecule improves stem cell homing; reproducible bacterial evolution; how human adaptive immunity develops
Reveling in the Revealed
Kelly Rae Chi | Jan 1, 2016 | 7 min read
A growing toolbox for surveying the activity of entire genomes
Beaker with glowing moneybag
New HHMI Investigator Cohort Announced
Chloe Tenn | Sep 23, 2021 | 3 min read
The Howard Hughes Medical Institute appoints 33 new researchers, each of whom will receive roughly $9 million over seven years.
Who Sleeps?
The Scientist and Jerome Siegel | Mar 1, 2016 | 10+ min read
Once believed to be unique to birds and mammals, sleep is found across the metazoan kingdom. Some animals, it seems, can’t live without it, though no one knows exactly why.
We Must Try To Bridge The Gap Between Biological And Chemical Sciences
Arthur Kornberg | Jul 24, 1988 | 8 min read
Chemical language has great asthetic beauty and links the physical sciences to the biological sciences. Unfortunately, the full use of this language to understand life processes is hindered by a gulf that separates chemistry from biology. This gulf is not nearly as wide as that between the humanities and and sciences, on which C.P. Snow focused attention. Yet, chemistry and biology are two distinctive cultures and the rift between them Is serious, generally unappreciated, and counterproductive.
2018 Top 10 Innovations
The Scientist | Dec 1, 2018 | 10+ min read
Biology happens on many levels, from ecosystems to electron transport chains. These tools may help spur discoveries at all of life's scales.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.

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