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image: Designing In Vitro Models of the Blood-Brain Barrier

Designing In Vitro Models of the Blood-Brain Barrier

By | September 1, 2016

Choosing the right model, be it 3-D or 2-D, requires wading through varied cell sources, cell types, and cell culture conditions.

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image: Promoting Protein Partnerships

Promoting Protein Partnerships

By | September 1, 2016

Scientists generate new protein-protein interactions at an impressive PACE.

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image: The Challenges of Rare-Disease Research

The Challenges of Rare-Disease Research

By | September 1, 2016

With few resources and hesitant investors, basic scientists must rely on clinicians, patient advocates, and their own keen eye for biological connections.

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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: Protein or Perish

Protein or Perish

By | September 1, 2016

A bacteriophage must evolve certain variants of a protein or die.

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image: One Receptor, Two Ligands, Different Responses

One Receptor, Two Ligands, Different Responses

By | August 31, 2016

Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 

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image: One Antigen Receptor Induces Two T cell Types

One Antigen Receptor Induces Two T cell Types

By | August 26, 2016

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

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image: Extinct River Dolphin Species Discovered

Extinct River Dolphin Species Discovered

By | August 16, 2016

Overlooked for half a century, a skull in the Smithsonian collection points to a dolphin species that lived 25 million years ago, according to a study.

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image: Using RNA to Amplify RNA

Using RNA to Amplify RNA

By | August 15, 2016

Researchers apply in vitro evolution to generate an RNA enzyme capable of copying and amplifying RNA.

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image: Polio Reemerges in Nigeria

Polio Reemerges in Nigeria

By | August 15, 2016

Prior to last week’s announcement of newly confirmed cases, the country had been polio-free for two years.

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