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tag hiv pathogenesis neuroscience microbiology genetics genomics

Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Microscope image of A549-ACE2 lung cells coinfected with SARS-CoV-2 and a reporter vector containing a key regulatory variant of interest in the region on human chromosome 3
How Genes from Neanderthals Predispose People to Severe COVID-19
Alakananda Dasgupta | Feb 22, 2023 | 4 min read
Researchers dissect the Neanderthal-derived region on chromosome 3 that drives severe COVID-19 to zero in on the key causal variants.
a close-up photo of C. elegans worms
Eyeless C. elegans Perceives Colors: Study
Shawna Williams | Mar 4, 2021 | 4 min read
The roundworm uses cues from visible light to help avoid eating toxic bacteria with a distinguishing hue.
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
A silver tree showing roots and branches in a circle on a blue background.
Onward and Upward!
Kristie Nybo, PhD | Sep 8, 2023 | 9 min read
At The Scientist, we are strengthening our roots while reaching for the sky.
Research Notes
Kate Devine | Oct 1, 2000 | 5 min read
HIV Hitches a Ride The statistics are grim: More than 34 million people worldwide affected with HIV/AIDS, and 800,000- 900,000 cases in the United States with a steady rate of 40,000 new HIV infections each year. Fueled by such statistics, HIV research continues with scientists at the National Institute of Allergy and Infectious Diseases (NIAID) recently discovering a mechanism providing insight into the pathogenesis of the virus in which HIV may hitch a ride from select cells to target cells.
The Genes of Parkinson’s Disease
Bobby Thomas and M. Flint Beal | Feb 1, 2011 | 10 min read
The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.
Those We Lost in 2019
Ashley Yeager | Dec 30, 2019 | 6 min read
The scientific community said goodbye to Sydney Brenner, Paul Greengard, Patricia Bath, and a number of other leading researchers this year.
The Body’s Ecosystem
The Scientist | Aug 1, 2014 | 10+ min read
Research on the human microbiome is booming, and scientists have moved from simply taking stock of gut flora to understanding the influence of microbes throughout the body.

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