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tag hiv pathogenesis genetics genomics cell molecular biology microbiology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Microscope image of A549-ACE2 lung cells coinfected with SARS-CoV-2 and a reporter vector containing a key regulatory variant of interest in the region on human chromosome 3
How Genes from Neanderthals Predispose People to Severe COVID-19
Alakananda Dasgupta | Feb 22, 2023 | 4 min read
Researchers dissect the Neanderthal-derived region on chromosome 3 that drives severe COVID-19 to zero in on the key causal variants.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
The Scientist Staff | Mar 28, 2024
Top 7 in Genomics & Genetics
Sabrina Richards | Sep 19, 2011 | 3 min read
A snapshot of the most highly ranked articles in genomics, genetics and related areas, from Faculty of 1000
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Research Notes
Kate Devine | Oct 1, 2000 | 5 min read
HIV Hitches a Ride The statistics are grim: More than 34 million people worldwide affected with HIV/AIDS, and 800,000- 900,000 cases in the United States with a steady rate of 40,000 new HIV infections each year. Fueled by such statistics, HIV research continues with scientists at the National Institute of Allergy and Infectious Diseases (NIAID) recently discovering a mechanism providing insight into the pathogenesis of the virus in which HIV may hitch a ride from select cells to target cells.
Are Phages Overlooked Mediators of Health and Disease?
Catherine Offord | Feb 1, 2021 | 10+ min read
Bacteria-infecting viruses affect the composition and behavior of microbes in the mammalian gut—and perhaps influence human biology.
A silver tree showing roots and branches in a circle on a blue background.
Onward and Upward!
Kristie Nybo, PhD | Sep 8, 2023 | 9 min read
At The Scientist, we are strengthening our roots while reaching for the sky.

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